Drug-related mortality and its impact on adult mortality in eight European countries

Objective: To estimate the mortality rates from drug-related deaths and other causes among problem drug users and population attributable risk of death due to opiate use in eight study sites in Europe. Methods: Opiate users were recruited from drug treatment centres during the period 1990–1998 and d...

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Published in:European journal of public health 2006-04, Vol.16 (2), p.198-202
Main Authors: Bargagli, Anna Maria, Hickman, Matthew, Davoli, Marina, Perucci, Carlo A., Schifano, Patrizia, Buster, Marcel, Brugal, Teresa, Vicente, Julian
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Adolescent
Adult
Age groups
AIDS
Cohort analysis
Drug addiction
Drug addicts
Drug use
drug-related mortality
Epidemiology
Estimates
Europe - epidemiology
European Union
Female
HIV
HIV positive persons
Human immunodeficiency virus
Humans
Longitudinal studies
Male
Males
Middle Aged
Mortality
Mortality - trends
Narcotics
opiate addiction
Opioid-Related Disorders - mortality
Poisoning
Population
Predation
Public health
Registries
Substance abuse treatment
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cited_by cdi_FETCH-LOGICAL-c426t-da92caeee99f37436831ec8bc155788aecaae39026ffe8d997128e55e82952033
cites cdi_FETCH-LOGICAL-c426t-da92caeee99f37436831ec8bc155788aecaae39026ffe8d997128e55e82952033
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container_issue 2
container_start_page 198
container_title European journal of public health
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creator Bargagli, Anna Maria
Hickman, Matthew
Davoli, Marina
Perucci, Carlo A.
Schifano, Patrizia
Buster, Marcel
Brugal, Teresa
Vicente, Julian
description Objective: To estimate the mortality rates from drug-related deaths and other causes among problem drug users and population attributable risk of death due to opiate use in eight study sites in Europe. Methods: Opiate users were recruited from drug treatment centres during the period 1990–1998 and deaths followed up through national or local mortality registries. Gender-specific overall mortality rate, proportion of deaths by cause (drug-related, HIV, other), standardized mortality ratios (SMRs), and the attributable risk fraction (ARF) were estimated. Results: Crude mortality rates varied from 1 per 100 person-years in the Dublin and London cohorts to 3.8 per 100 person-years in Barcelona. The highest drug-related mortality rate was 10 per 1000 person-years in Barcelona; the rates were ∼7 per 1000 person-years in Denmark, London, Rome, and Vienna, and
doi_str_mv 10.1093/eurpub/cki168
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Methods: Opiate users were recruited from drug treatment centres during the period 1990–1998 and deaths followed up through national or local mortality registries. Gender-specific overall mortality rate, proportion of deaths by cause (drug-related, HIV, other), standardized mortality ratios (SMRs), and the attributable risk fraction (ARF) were estimated. Results: Crude mortality rates varied from 1 per 100 person-years in the Dublin and London cohorts to 3.8 per 100 person-years in Barcelona. The highest drug-related mortality rate was 10 per 1000 person-years in Barcelona; the rates were ∼7 per 1000 person-years in Denmark, London, Rome, and Vienna, and &lt;3.5 per 1000 person-years for the others cohorts. The mortality rate for AIDS was &lt;2 per 1000 person-years in all the cohorts except Lisbon, Rome, and Barcelona, for which it was ∼6 per 1000 person-years. The highest SMR among males was 21.1 in Barcelona, and among females the highest SMRs were 53.7 and 37.7 in Barcelona and Rome, respectively. In Denmark the ARF was 5%, whereas it was &gt;10% in all other study sites and 24% in Barcelona. Conclusion: Cohort mortality studies, especially in combination with estimates of prevalence, provide useful insights into the impact of opiate use on mortality across European countries and emphasize how preventing overall and drug-related deaths among opiate users can significantly improve the health of the population.</description><identifier>ISSN: 1101-1262</identifier><identifier>EISSN: 1464-360X</identifier><identifier>DOI: 10.1093/eurpub/cki168</identifier><identifier>PMID: 16157612</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Acquired immune deficiency syndrome ; Adolescent ; Adult ; Age groups ; AIDS ; Cohort analysis ; Drug addiction ; Drug addicts ; Drug use ; drug-related mortality ; Epidemiology ; Estimates ; Europe - epidemiology ; European Union ; Female ; HIV ; HIV positive persons ; Human immunodeficiency virus ; Humans ; Longitudinal studies ; Male ; Males ; Middle Aged ; Mortality ; Mortality - trends ; Narcotics ; opiate addiction ; Opioid-Related Disorders - mortality ; Poisoning ; Population ; Predation ; Public health ; Registries ; Substance abuse treatment</subject><ispartof>European journal of public health, 2006-04, Vol.16 (2), p.198-202</ispartof><rights>Copyright Oxford University Press(England) Apr 2006</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c426t-da92caeee99f37436831ec8bc155788aecaae39026ffe8d997128e55e82952033</citedby><cites>FETCH-LOGICAL-c426t-da92caeee99f37436831ec8bc155788aecaae39026ffe8d997128e55e82952033</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27865,27866,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16157612$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bargagli, Anna Maria</creatorcontrib><creatorcontrib>Hickman, Matthew</creatorcontrib><creatorcontrib>Davoli, Marina</creatorcontrib><creatorcontrib>Perucci, Carlo A.</creatorcontrib><creatorcontrib>Schifano, Patrizia</creatorcontrib><creatorcontrib>Buster, Marcel</creatorcontrib><creatorcontrib>Brugal, Teresa</creatorcontrib><creatorcontrib>Vicente, Julian</creatorcontrib><creatorcontrib>COSMO European Group</creatorcontrib><title>Drug-related mortality and its impact on adult mortality in eight European countries</title><title>European journal of public health</title><addtitle>Eur J Public Health</addtitle><description>Objective: To estimate the mortality rates from drug-related deaths and other causes among problem drug users and population attributable risk of death due to opiate use in eight study sites in Europe. Methods: Opiate users were recruited from drug treatment centres during the period 1990–1998 and deaths followed up through national or local mortality registries. Gender-specific overall mortality rate, proportion of deaths by cause (drug-related, HIV, other), standardized mortality ratios (SMRs), and the attributable risk fraction (ARF) were estimated. Results: Crude mortality rates varied from 1 per 100 person-years in the Dublin and London cohorts to 3.8 per 100 person-years in Barcelona. The highest drug-related mortality rate was 10 per 1000 person-years in Barcelona; the rates were ∼7 per 1000 person-years in Denmark, London, Rome, and Vienna, and &lt;3.5 per 1000 person-years for the others cohorts. The mortality rate for AIDS was &lt;2 per 1000 person-years in all the cohorts except Lisbon, Rome, and Barcelona, for which it was ∼6 per 1000 person-years. The highest SMR among males was 21.1 in Barcelona, and among females the highest SMRs were 53.7 and 37.7 in Barcelona and Rome, respectively. In Denmark the ARF was 5%, whereas it was &gt;10% in all other study sites and 24% in Barcelona. 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The highest SMR among males was 21.1 in Barcelona, and among females the highest SMRs were 53.7 and 37.7 in Barcelona and Rome, respectively. In Denmark the ARF was 5%, whereas it was &gt;10% in all other study sites and 24% in Barcelona. Conclusion: Cohort mortality studies, especially in combination with estimates of prevalence, provide useful insights into the impact of opiate use on mortality across European countries and emphasize how preventing overall and drug-related deaths among opiate users can significantly improve the health of the population.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>16157612</pmid><doi>10.1093/eurpub/cki168</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
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source Oxford Journals Open Access Collection; PAIS Index
subjects Acquired immune deficiency syndrome
Adolescent
Adult
Age groups
AIDS
Cohort analysis
Drug addiction
Drug addicts
Drug use
drug-related mortality
Epidemiology
Estimates
Europe - epidemiology
European Union
Female
HIV
HIV positive persons
Human immunodeficiency virus
Humans
Longitudinal studies
Male
Males
Middle Aged
Mortality
Mortality - trends
Narcotics
opiate addiction
Opioid-Related Disorders - mortality
Poisoning
Population
Predation
Public health
Registries
Substance abuse treatment
title Drug-related mortality and its impact on adult mortality in eight European countries
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