Association of splenectomy with postoperative complications in patients with proximal gastric and gastroesophageal junction cancer

Splenectomy has been associated with increased morbidity after gastrectomy for gastric cancer. Resection of proximal versus distal tumors is associated with a higher morbidity. Because splenectomy is more commonly performed in resection of proximal tumors, these analyses may be biased. The aim of th...

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Bibliographic Details
Published in:Annals of surgical oncology 2004-07, Vol.11 (7), p.682-689
Main Authors: Weitz, Jürgen, Jaques, David P, Brennan, Murray, Karpeh, Martin
Format: Article
Language:English
Subjects:
Adenocarcinoma - surgery
Adult
Aged
Aged, 80 and over
Databases, Factual
Esophageal Neoplasms - surgery
Esophagogastric Junction - pathology
Esophagogastric Junction - surgery
Female
Humans
Male
Middle Aged
Morbidity
Postoperative Complications
Prospective Studies
Risk Factors
Splenectomy - adverse effects
Stomach Neoplasms - surgery
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Summary:Splenectomy has been associated with increased morbidity after gastrectomy for gastric cancer. Resection of proximal versus distal tumors is associated with a higher morbidity. Because splenectomy is more commonly performed in resection of proximal tumors, these analyses may be biased. The aim of this study was to describe the association of splenectomy with complications in patients undergoing resection of proximal gastric and gastroesophageal junction (GEJ) cancers. From July 1985 to August 2001, 335 patients underwent resection of proximal gastric or GEJ (type II and III) cancers. Clinical and pathologic factors were retrieved from a prospective database. Overall morbidity was 59% (infectious complications, 41%; noninfectious complications, 36%), and mortality was 4.5%. Splenectomy was associated with a higher rate of infectious complications (57% vs. 33%; P
ISSN:1068-9265
1534-4681
DOI:10.1245/ASO.2004.03.048