Prevalence of human immunodeficiency virus infection in children with tuberculosis

This prospective study was carried out in the pediatric ward and outpatient department of a tertiary care centre to estimate the prevalence of HIV seropositivity in children with tuberculosis. Two hundred and fifty consecutive children below 12 years of age with (pulmonary and extrapulmonary) tuberc...

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Bibliographic Details
Published in:Indian pediatrics 2004-06, Vol.41 (6), p.595-599
Main Authors: SHAHAB, T, ZOHA, M. S, MALIK, M. Ashraf, MALIK, Abida, AFZAL, K
Format: Article
Language:English
Subjects:
AIDS-Related Opportunistic Infections - complications
AIDS-Related Opportunistic Infections - epidemiology
Bacterial diseases
Biological and medical sciences
Child
Child, Preschool
Female
HIV Infections - complications
HIV Infections - epidemiology
HIV Seroprevalence
Human bacterial diseases
Human viral diseases
Humans
India - epidemiology
Infant
Infant, Newborn
Infectious diseases
Male
Medical sciences
Tuberculosis - complications
Tuberculosis - epidemiology
Tuberculosis and atypical mycobacterial infections
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
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Summary:This prospective study was carried out in the pediatric ward and outpatient department of a tertiary care centre to estimate the prevalence of HIV seropositivity in children with tuberculosis. Two hundred and fifty consecutive children below 12 years of age with (pulmonary and extrapulmonary) tuberculosis diagnosed between March 1999 and July 2000 were screened for HIV infection. A patient was labeled as HIV positive if two consecutive ELISA tests were found positive using different antigen/principle. Supplemental western blot test was also done. Parents of seropositive children were also screened for HIV infection and tuberculosis. Total 5 cases were HIV positive giving a seroprevalence of 2%. All the five patients had disseminated tuberculosis. We suggest regular screening of children with disseminated/miliary tuberculosis for HIV co-infection.
ISSN:0019-6061
0974-7559