MR imaging of infiltrative muscle involvement with Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) consists of three clinical syndromes of varying severity resulting from basic cellular defect leading to lipid deposition within histiocytes. Radiologically, bone lesions are similar in all three forms of LCH and are due to bone destruction. An eosinophilic granul...

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Bibliographic Details
Published in:Clinical imaging 2004-07, Vol.28 (4), p.301-304
Main Authors: May, David A, Kaushik, Shaifali, Frable, William J
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biopsy, Needle
Contrast Media
Diagnosis, Differential
Eosinophilic granuloma
Female
Follow-Up Studies
Hematologic and hematopoietic diseases
Histiocytosis, Langerhans-Cell - diagnosis
Humans
Image Enhancement
Investigative techniques, diagnostic techniques (general aspects)
Langerhans cell histiocytosis
LCH
Lymphoma
Magnetic Resonance Imaging
Medical sciences
Middle Aged
MR imaging
Muscular Diseases - diagnosis
Muscular system
Musculoskeletal system
Nodular muscle lesions
Other diseases. Hematologic involvement in other diseases
Radiation therapy
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Recurrence
Rotator Cuff - pathology
Shoulder
Tumors
Weightlifting
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Summary:Langerhans cell histiocytosis (LCH) consists of three clinical syndromes of varying severity resulting from basic cellular defect leading to lipid deposition within histiocytes. Radiologically, bone lesions are similar in all three forms of LCH and are due to bone destruction. An eosinophilic granuloma of the bone can involve skeletal muscle by direct extension from the bone. However, skeletal muscle involvement is rare and is not reported on MR imaging previously in the English literature. Our case not only shows biopsy-proven muscle involvement by LCH but also reports the first diffuse nodular pattern of muscle involvement by LCH.
ISSN:0899-7071
1873-4499
DOI:10.1016/S0899-7071(03)00194-3