Morphological changes in intervertabral disk tissues in a static asymmetrical compression model of degenerative dystrophic diseases of intervertabral disks

Morphological studies showed that the model of compression static asymmetric degenerative diseases of intervertebral disks in rats developed by us corresponds to degenerative diseases of the spine in humans. Three-month compression led to a significant reduction of the total disk height by 15.3% and...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2008-09, Vol.146 (3), p.361-365
Main Authors: Volkov, A. V, Bol'shakova, G. B, Goldstein, D. V
Format: Article
Language:English
Subjects:
Animals
Biomedical and Life Sciences
Biomedicine
Cell Biology
Disease Models, Animal
Internal Medicine
intervertabral disk
Intervertebral Disc - pathology
Laboratory Medicine
Male
Morphology and Pathomorphology
osteochondrosis
Pathology
Pressure
Rats
Rats, Wistar
Spinal Diseases - pathology
tail
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Summary:Morphological studies showed that the model of compression static asymmetric degenerative diseases of intervertebral disks in rats developed by us corresponds to degenerative diseases of the spine in humans. Three-month compression led to a significant reduction of the total disk height by 15.3% and a reduction in the content of notochondrial cells by 64.8%.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-008-0290-4