A paucity of structural integrity in cloned porcine blastocysts produced in vitro

The structural integrity of blastocyst stage embryos, consisting of the inner cell mass (ICM) and trophectoderm (TE) cells, is a prerequisite for normal development after implantation in mammals. In this study, allocation of nuclear transfer (NT)-derived porcine blastocysts to the ICM and to the TE...

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Bibliographic Details
Published in:Theriogenology 2004-09, Vol.62 (5), p.779-789
Main Authors: Koo, Deog-Bon, Kang, Yong-Kook, Park, Jung Sun, Park, Jin-Ki, Chang, Won-Kyong, Lee, Kyung-Kwang, Han, Yong-Mahn
Format: Article
Language:English
Subjects:
Animals
Blastocyst
Blastocyst - cytology
Blastocyst - physiology
Cell Count
Cloning, Organism
Differential staining
embryo culture
embryogenesis
embryonic mortality
embryonic structures
Female
Fertilization in Vitro - veterinary
In vitro fertilization
inner cell mass
Male
Nuclear transfer
Nuclear Transfer Techniques
nuclear transplantation
Porcine
Swine
trophectoderm
trophoblast
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Summary:The structural integrity of blastocyst stage embryos, consisting of the inner cell mass (ICM) and trophectoderm (TE) cells, is a prerequisite for normal development after implantation in mammals. In this study, allocation of nuclear transfer (NT)-derived porcine blastocysts to the ICM and to the TE cells was examined and compared with IVF- and in vivo-derived embryos. NT-derived embryos had a lower developmental competence to the blastocyst stage than IVF-derived embryos ( P
ISSN:0093-691X
1879-3231
DOI:10.1016/j.theriogenology.2003.12.027