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Endovascular cerebral aneurysm treatment : Long-term outcomes
The International Subarachnoid Aneurysm Trial confirmed endovascular treatment as the treatment of choice for intracranial 'berry' aneurysms. The durability of coiling and the relevance of stable neck remnants needed to be addressed next. We retrospectively assessed the follow-up angiogram...
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Published in: | South African medical journal 2008-12, Vol.98 (12), p.954-957 |
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description | The International Subarachnoid Aneurysm Trial confirmed endovascular treatment as the treatment of choice for intracranial 'berry' aneurysms. The durability of coiling and the relevance of stable neck remnants needed to be addressed next.
We retrospectively assessed the follow-up angiograms of patients who presented with subarachnoid haemorrhages or third-nerve palsies and had berry aneurysms treated endovascularly between 2002 and 2003. Patients were phoned to assess their wellbeing and to see whether they were back at work or not. Angiograms were assessed to ascertain the percentage of the aneurysm coiled at the initial procedure, and then stability was assessed by percentage change in the residual aneuysm neck on later angiograms.
Over a 1-year period 75 patients were treated endovascularly; 100% occlusion was achieved in 52% at the initial procedure, and although only 40 and 34 respectively attended for 3-month and 1-year follow-up angiograms there was a trend toward progressive thrombosis in 65% and 82% respectively. In only 1 of the neck remnants was growth noted at the 3-month angiogram. One patient bled after missing his 3-month follow-up angiogram. Although only 40% of the patients were contactable at 4 years there were no rebleeds among them.
Coiling is durable, as shown by our results over a 4-year period, and while neck remnants that look unchanged are generally stable any growth should be viewed as grounds for concern and treated either endovascularly or surgically if required. The 5-year angiogram may be unnecessary, which is of importance in our setting where socio-economic factors influence patient follow-up. |
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We retrospectively assessed the follow-up angiograms of patients who presented with subarachnoid haemorrhages or third-nerve palsies and had berry aneurysms treated endovascularly between 2002 and 2003. Patients were phoned to assess their wellbeing and to see whether they were back at work or not. Angiograms were assessed to ascertain the percentage of the aneurysm coiled at the initial procedure, and then stability was assessed by percentage change in the residual aneuysm neck on later angiograms.
Over a 1-year period 75 patients were treated endovascularly; 100% occlusion was achieved in 52% at the initial procedure, and although only 40 and 34 respectively attended for 3-month and 1-year follow-up angiograms there was a trend toward progressive thrombosis in 65% and 82% respectively. In only 1 of the neck remnants was growth noted at the 3-month angiogram. One patient bled after missing his 3-month follow-up angiogram. Although only 40% of the patients were contactable at 4 years there were no rebleeds among them.
Coiling is durable, as shown by our results over a 4-year period, and while neck remnants that look unchanged are generally stable any growth should be viewed as grounds for concern and treated either endovascularly or surgically if required. The 5-year angiogram may be unnecessary, which is of importance in our setting where socio-economic factors influence patient follow-up.</description><identifier>ISSN: 0256-9574</identifier><identifier>PMID: 19374073</identifier><identifier>CODEN: SAMJAF</identifier><language>eng</language><publisher>Rondebosch: Health and Medical Publishing Group</publisher><subject>Angiography ; Angioscopy - methods ; Biological and medical sciences ; Care and treatment ; Diagnosis ; Endovascular stents ; Follow-Up Studies ; General aspects ; Health aspects ; Humans ; Intracranial Aneurysm - diagnostic imaging ; Intracranial Aneurysm - surgery ; Intracranial aneurysms ; Medical sciences ; Neurology ; Patient outcomes ; Retrospective Studies ; Time Factors ; Treatment Outcome ; Vascular diseases and vascular malformations of the nervous system</subject><ispartof>South African medical journal, 2008-12, Vol.98 (12), p.954-957</ispartof><rights>2009 INIST-CNRS</rights><rights>COPYRIGHT 2008 Health & Medical Publishing Group</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21055695$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19374073$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LE FEUVRE, David E</creatorcontrib><creatorcontrib>TAYLOR, Allan G</creatorcontrib><title>Endovascular cerebral aneurysm treatment : Long-term outcomes</title><title>South African medical journal</title><addtitle>S Afr Med J</addtitle><description>The International Subarachnoid Aneurysm Trial confirmed endovascular treatment as the treatment of choice for intracranial 'berry' aneurysms. The durability of coiling and the relevance of stable neck remnants needed to be addressed next.
We retrospectively assessed the follow-up angiograms of patients who presented with subarachnoid haemorrhages or third-nerve palsies and had berry aneurysms treated endovascularly between 2002 and 2003. Patients were phoned to assess their wellbeing and to see whether they were back at work or not. Angiograms were assessed to ascertain the percentage of the aneurysm coiled at the initial procedure, and then stability was assessed by percentage change in the residual aneuysm neck on later angiograms.
Over a 1-year period 75 patients were treated endovascularly; 100% occlusion was achieved in 52% at the initial procedure, and although only 40 and 34 respectively attended for 3-month and 1-year follow-up angiograms there was a trend toward progressive thrombosis in 65% and 82% respectively. In only 1 of the neck remnants was growth noted at the 3-month angiogram. One patient bled after missing his 3-month follow-up angiogram. Although only 40% of the patients were contactable at 4 years there were no rebleeds among them.
Coiling is durable, as shown by our results over a 4-year period, and while neck remnants that look unchanged are generally stable any growth should be viewed as grounds for concern and treated either endovascularly or surgically if required. The 5-year angiogram may be unnecessary, which is of importance in our setting where socio-economic factors influence patient follow-up.</description><subject>Angiography</subject><subject>Angioscopy - methods</subject><subject>Biological and medical sciences</subject><subject>Care and treatment</subject><subject>Diagnosis</subject><subject>Endovascular stents</subject><subject>Follow-Up Studies</subject><subject>General aspects</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Intracranial Aneurysm - diagnostic imaging</subject><subject>Intracranial Aneurysm - surgery</subject><subject>Intracranial aneurysms</subject><subject>Medical sciences</subject><subject>Neurology</subject><subject>Patient outcomes</subject><subject>Retrospective Studies</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>Vascular diseases and vascular malformations of the nervous system</subject><issn>0256-9574</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNpt0EtLAzEQAOA9KLZW_4IsiL2t5LFJuoKHUuoDCl70vGSzk3Ylm9QkK_TfG2kVCzKHYTLfhGFOsjEijBcVE-UoOw_hHaWaVfwsG-GKihIJOs7ul7Z1nzKowUifK_DQeGlyaWHwu9Dn0YOMPdiY3-UrZ9dFBN_nbojK9RAuslMtTYDLQ55kbw_L18VTsXp5fF7MV8WaCh4LXmEtuaKAVKuIrAhmDJesEYRopXWJG4HEDIvU0iW0lJSMgmiBt6UkM43pJJvu_9169zFAiHXfBQXGpD3dEGrOBcaEogSv93AtDdSd1S56qb5xPSeoZAzN2Cyp239Uihb6TjkLukvvRwPTPwMbkCZugjND7JwNx_DqsOjQ9NDWW9_10u_qn4MncHMA6ebSaC-t6sKvIxgxxitGvwBV5oV_</recordid><startdate>20081201</startdate><enddate>20081201</enddate><creator>LE FEUVRE, David E</creator><creator>TAYLOR, Allan G</creator><general>Health and Medical Publishing Group</general><general>Health & Medical Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20081201</creationdate><title>Endovascular cerebral aneurysm treatment : Long-term outcomes</title><author>LE FEUVRE, David E ; TAYLOR, Allan G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g376t-691fa6c3e0cdc2a92155145b722fcff41b7078172a9f4ed32453e7de6d4a28f13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Angiography</topic><topic>Angioscopy - methods</topic><topic>Biological and medical sciences</topic><topic>Care and treatment</topic><topic>Diagnosis</topic><topic>Endovascular stents</topic><topic>Follow-Up Studies</topic><topic>General aspects</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Intracranial Aneurysm - diagnostic imaging</topic><topic>Intracranial Aneurysm - surgery</topic><topic>Intracranial aneurysms</topic><topic>Medical sciences</topic><topic>Neurology</topic><topic>Patient outcomes</topic><topic>Retrospective Studies</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Vascular diseases and vascular malformations of the nervous system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LE FEUVRE, David E</creatorcontrib><creatorcontrib>TAYLOR, Allan G</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>South African medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LE FEUVRE, David E</au><au>TAYLOR, Allan G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Endovascular cerebral aneurysm treatment : Long-term outcomes</atitle><jtitle>South African medical journal</jtitle><addtitle>S Afr Med J</addtitle><date>2008-12-01</date><risdate>2008</risdate><volume>98</volume><issue>12</issue><spage>954</spage><epage>957</epage><pages>954-957</pages><issn>0256-9574</issn><coden>SAMJAF</coden><abstract>The International Subarachnoid Aneurysm Trial confirmed endovascular treatment as the treatment of choice for intracranial 'berry' aneurysms. The durability of coiling and the relevance of stable neck remnants needed to be addressed next.
We retrospectively assessed the follow-up angiograms of patients who presented with subarachnoid haemorrhages or third-nerve palsies and had berry aneurysms treated endovascularly between 2002 and 2003. Patients were phoned to assess their wellbeing and to see whether they were back at work or not. Angiograms were assessed to ascertain the percentage of the aneurysm coiled at the initial procedure, and then stability was assessed by percentage change in the residual aneuysm neck on later angiograms.
Over a 1-year period 75 patients were treated endovascularly; 100% occlusion was achieved in 52% at the initial procedure, and although only 40 and 34 respectively attended for 3-month and 1-year follow-up angiograms there was a trend toward progressive thrombosis in 65% and 82% respectively. In only 1 of the neck remnants was growth noted at the 3-month angiogram. One patient bled after missing his 3-month follow-up angiogram. Although only 40% of the patients were contactable at 4 years there were no rebleeds among them.
Coiling is durable, as shown by our results over a 4-year period, and while neck remnants that look unchanged are generally stable any growth should be viewed as grounds for concern and treated either endovascularly or surgically if required. The 5-year angiogram may be unnecessary, which is of importance in our setting where socio-economic factors influence patient follow-up.</abstract><cop>Rondebosch</cop><pub>Health and Medical Publishing Group</pub><pmid>19374073</pmid><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Angiography Angioscopy - methods Biological and medical sciences Care and treatment Diagnosis Endovascular stents Follow-Up Studies General aspects Health aspects Humans Intracranial Aneurysm - diagnostic imaging Intracranial Aneurysm - surgery Intracranial aneurysms Medical sciences Neurology Patient outcomes Retrospective Studies Time Factors Treatment Outcome Vascular diseases and vascular malformations of the nervous system |
title | Endovascular cerebral aneurysm treatment : Long-term outcomes |
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