Improvement in Survival Following Successful Percutaneous Coronary Intervention of Coronary Chronic Total Occlusions: Variability by Target Vessel

• Published in: JACC. Cardiovascular interventions 2008-06, Vol.1 (3), p.295-302
• Main Authors: Safley, David M., MD, FACC, House, John A., MS, Marso, Steven P., MD, FACC, Grantham, J. Aaron, MD, FACC, Rutherford, Barry D., MD, FACC
• Format: Article
• Language: English
• Subjects: Aged; Angioplasty, Balloon, Coronary - adverse effects; Angioplasty, Balloon, Coronary - mortality; Cardiovascular; Chronic Disease; Coronary Angiography; Coronary Occlusion - diagnostic imaging; Coronary Occlusion - mortality; Coronary Occlusion - therapy; Female; Heart Diseases - etiology; Heart Diseases - mortality; Hospital Mortality; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Patient Selection; Platelet Aggregation Inhibitors - therapeutic use; Proportional Hazards Models; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome
• ISSN: 1936-8798; 1876-7605
• DOI: 10.1016/j.jcin.2008.05.004

Improvement in Survival Following Successful Percutaneous Coronary Intervention of Coronary Chronic Total Occlusions: Variability by Target Vessel David M. Safley, John A. House, Steven P. Marso, J. Aaron Grantham, Barry D. Rutherford This study compared the survival benefits of successful chronic total occlusion (CTO) percutaneous coronary intervention (PCI) of the left anterior descending (LAD), left circumflex, or right coronary artery. Eligible patients underwent single vessel PCI. The primary end point was 5-year survival, compared across target vessel groups stratified by procedural success. Of 2,608 patients, the LAD was the target in 936 (36%), the left circumflex in 682 (26%), and the right coronary artery in 990 (38%). In multivariable analysis, CTO PCI success of the LAD was associated with decreased mortality (HR: 0.61, 95% CI: 0.42 to 0.89). This information may assist in selecting patients for CTO PCI.