Study of Efficiency of Therapeutic and Preventive Anaferon (Pediatric Formulation) in Mice with Influenza Infection

Therapeutic and preventive treatment of mice intranasally infected with a lethal dose of A/Aichi/2/68 (H3N2) influenza virus with anaferon (pediatric formulation) demonstrated an antiviral effect of the drug (increased percent of survivors and prolonged lifespan).

Saved in:
Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2008-12, Vol.146 (6), p.763-765
Main Authors: Shishkina, L. N., Sergeev, A. N., Kabanov, A. S., Skarnovich, M. O., Evtin, N. K., Mazurkova, N. A., Sergeev, A. A., Belopolskaya, M. V., Kheyfets, I. A., Dugina, J. L., Tarasov, S. A., Sergeeva, S. A., Epstein, O. I.
Format: Article
Language:English
Subjects:
Administration, Intranasal
Animals
Antiviral Agents - therapeutic use
Biomedical and Life Sciences
Biomedicine
Cell Biology
Dose-Response Relationship, Drug
Female
Influenza A Virus, H3N2 Subtype - drug effects
Influenza A Virus, H3N2 Subtype - pathogenicity
Influenza virus
Interferon-gamma - immunology
Internal Medicine
Laboratory Medicine
Mice
Mice, Inbred BALB C
Orthomyxoviridae Infections - drug therapy
Orthomyxoviridae Infections - immunology
Orthomyxoviridae Infections - mortality
Oseltamivir - therapeutic use
Pathology
Virology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Therapeutic and preventive treatment of mice intranasally infected with a lethal dose of A/Aichi/2/68 (H3N2) influenza virus with anaferon (pediatric formulation) demonstrated an antiviral effect of the drug (increased percent of survivors and prolonged lifespan).
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-009-0378-5