Bilateral intraneural perineurioma presenting as ulnar neuropathy at the elbow

We describe a 36‐year‐old woman with progressive bilateral ulnar neuropathy. Sonographic and magnetic resonance imaging studies revealed extensive focal ulnar nerve enlargement at the elbow. Histological studies gave evidence of an intraneural perineurioma. Because intraneural perineurioma usually a...

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Bibliographic Details
Published in:Muscle & nerve 2004-08, Vol.30 (2), p.239-243
Main Authors: Beekman, Roy, Slooff, Willem-Bart M., Van Oosterhout, Matthijs F. M., Lammens, Martin, Van Den Berg, Leonard H.
Format: Article
Language:English
Subjects:
Action Potentials
Adult
Biological and medical sciences
Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction
Diagnosis, Differential
Elbow
Electrodiagnosis
Electromyography
Female
Humans
imaging studies
Magnetic Resonance Imaging
Medical sciences
nerve enlargement
nerve hypertrophy
Nerve Sheath Neoplasms - complications
Nerve Sheath Neoplasms - diagnosis
Nerve Sheath Neoplasms - pathology
Nervous system (semeiology, syndromes)
Neurology
perineurioma
Peripheral Nervous System Neoplasms - complications
Peripheral Nervous System Neoplasms - diagnosis
Peripheral Nervous System Neoplasms - pathology
Ulnar Nerve - pathology
Ulnar Neuropathies - etiology
ulnar neuropathy
Ultrasonography
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Description
Summary:We describe a 36‐year‐old woman with progressive bilateral ulnar neuropathy. Sonographic and magnetic resonance imaging studies revealed extensive focal ulnar nerve enlargement at the elbow. Histological studies gave evidence of an intraneural perineurioma. Because intraneural perineurioma usually appears as a single mass lesion at sites other than typical entrapment sites, this mode of presentation is unusual. We discuss the nature of this benign tumor and the differential diagnosis of nerve enlargement. Knowledge of possible causes of nerve thickening is crucial when performing imaging in patients with neuropathies. Muscle Nerve 30: 239–243, 2004
ISSN:0148-639X
1097-4598
DOI:10.1002/mus.20052