Bilateral intraneural perineurioma presenting as ulnar neuropathy at the elbow

• Published in: Muscle & nerve 2004-08, Vol.30 (2), p.239-243
• Main Authors: Beekman, Roy, Slooff, Willem-Bart M., Van Oosterhout, Matthijs F. M., Lammens, Martin, Van Den Berg, Leonard H.
• Format: Article
• Language: English
• Subjects: Action Potentials; Adult; Biological and medical sciences; Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction; Diagnosis, Differential; Elbow; Electrodiagnosis; Electromyography; Female; Humans; imaging studies; Magnetic Resonance Imaging; Medical sciences; nerve enlargement; nerve hypertrophy; Nerve Sheath Neoplasms - complications; Nerve Sheath Neoplasms - diagnosis; Nerve Sheath Neoplasms - pathology; Nervous system (semeiology, syndromes); Neurology; perineurioma; Peripheral Nervous System Neoplasms - complications; Peripheral Nervous System Neoplasms - diagnosis; Peripheral Nervous System Neoplasms - pathology; Ulnar Nerve - pathology; Ulnar Neuropathies - etiology; ulnar neuropathy; Ultrasonography
• ISSN: 0148-639X; 1097-4598
• DOI: 10.1002/mus.20052

We describe a 36‐year‐old woman with progressive bilateral ulnar neuropathy. Sonographic and magnetic resonance imaging studies revealed extensive focal ulnar nerve enlargement at the elbow. Histological studies gave evidence of an intraneural perineurioma. Because intraneural perineurioma usually appears as a single mass lesion at sites other than typical entrapment sites, this mode of presentation is unusual. We discuss the nature of this benign tumor and the differential diagnosis of nerve enlargement. Knowledge of possible causes of nerve thickening is crucial when performing imaging in patients with neuropathies. Muscle Nerve 30: 239–243, 2004