Clinical and Prognostic Value of Duke's Activity Status Index Along With Plasma B-Type Natriuretic Peptide Levels in Chronic Heart Failure Secondary to Ischemic or Idiopathic Dilated Cardiomyopathy

The Duke Activity Status Index (DASI) provides an accurate estimate of functional capacity in patients with chronic heart failure (HF). The aim of this study was to evaluate the prognostic value of the DASI against well-established prognostic factors in 130 consecutive patients hospitalized for wors...

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Bibliographic Details
Published in:The American journal of cardiology 2009, Vol.103 (1), p.73-75
Main Authors: Parissis, John T., MD, Nikolaou, Maria, MD, Birmpa, Dionysia, MD, Farmakis, Dimitrios, MD, Paraskevaidis, Ioannis, MD, Bistola, Vassiliki, MD, Katsoulas, Theodoros, MS, Filippatos, Gerasimos, MD, Kremastinos, Dimitrios T., MD
Format: Article
Language:English
Subjects:
Activities of Daily Living
Biological and medical sciences
Cardiology
Cardiology. Vascular system
Cardiomyopathy, Dilated - blood
Cardiomyopathy, Dilated - complications
Cardiomyopathy, Dilated - physiopathology
Cardiovascular
Chronic Disease
Female
Follow-Up Studies
Heart
Heart failure
Heart Failure - blood
Heart Failure - etiology
Heart Failure - physiopathology
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Hospitalization
Humans
Male
Medical prognosis
Medical sciences
Middle Aged
Myocardial Ischemia - blood
Myocardial Ischemia - complications
Myocardial Ischemia - physiopathology
Myocarditis. Cardiomyopathies
Natriuretic Peptide, Brain - blood
Peptides
Prognosis
Quality of Life
Regression analysis
Stroke Volume - physiology
Studies
Survival analysis
Ventricular Function, Left - physiology
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Description
Summary:The Duke Activity Status Index (DASI) provides an accurate estimate of functional capacity in patients with chronic heart failure (HF). The aim of this study was to evaluate the prognostic value of the DASI against well-established prognostic factors in 130 consecutive patients hospitalized for worsening HF symptoms (mean age 64 ± 12 years, mean left ventricular ejection fraction 26 ± 7%), followed for 9 months for major cardiovascular events, defined as death or hospitalization for HF decompensation. During follow-up, 77 of 130 patients (59%) experienced major cardiovascular events after a median time of 60 days (range 5 to 220). Patients with eventful courses were in higher New York Heart Association functional classes (p = 0.001) and had shorter 6-minute walking distances (p = 0.041), lower ejection fractions (p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2008.08.045