Incomplete Kawasaki disease in patients younger than 1 year of age: a possible inherent risk factor

Kawasaki disease (KD) patients younger than 1 year of age are at especially high risk of developing coronary artery abnormalities (CAA). To define the clinical characteristics of this group, as well as the risk factors predisposing them to CAA, we reviewed the medical records of 136 KD patients youn...

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Bibliographic Details
Published in:European journal of pediatrics 2009-02, Vol.168 (2), p.157-162
Main Authors: Yeo, Yunku, Kim, TaeYeon, Ha, KeeSoo, Jang, GiYoung, Lee, JungHwa, Lee, KwangChul, Son, ChangSung, Lee, JooWon
Format: Article
Language:English
Subjects:
Age
Aspirin
Biological and medical sciences
Coronary Aneurysm - diagnosis
Coronary Aneurysm - drug therapy
Coronary Artery Disease - diagnosis
Coronary Artery Disease - drug therapy
Coronary vessels
Diagnosis, Differential
Dilatation, Pathologic - drug therapy
Epidemiology
Female
Fever
gamma-Globins - administration & dosage
General aspects
Humans
Infant
Infusions, Intravenous
Kawasaki disease
Male
Medical records
Medical sciences
Medicine
Medicine & Public Health
Mucocutaneous Lymph Node Syndrome - diagnosis
Mucocutaneous Lymph Node Syndrome - drug therapy
Original Paper
Pediatrics
Prognosis
Public health. Hygiene
Public health. Hygiene-occupational medicine
Regression analysis
Retrospective Studies
Risk Factors
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Veins & arteries
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Summary:Kawasaki disease (KD) patients younger than 1 year of age are at especially high risk of developing coronary artery abnormalities (CAA). To define the clinical characteristics of this group, as well as the risk factors predisposing them to CAA, we reviewed the medical records of 136 KD patients younger than 1 year of age who were treated at the Korea University Medical Center from January 2001 to July 2006. Of these patients, 16 developed CAA (11.8%). The CAA(+) group had a longer duration of total fever than the CAA(−) group (9.1±3.7 days vs. 6.3±2.0 days, p =0.011), but did not differ in the duration of pre- and post-intravenous gamma-globulin (IVGG) fever. The CAA(+) group had fewer diagnostic symptoms than the CAA(−) group (2.7±1.1 vs. 4.3±1.2, p
ISSN:0340-6199
1432-1076
DOI:10.1007/s00431-008-0722-1