Timing of voiding cystourethrography in infants with first time urinary infection

The aim of the study was to evaluate whether the timing of performing a voiding cystourethrography (VCUG) following a first urinary tract infection (UTI) in infants is related to the presence or the severity of vesicoureteral reflux (VUR). A total of 411 children (male 230, female 181) with a first-...

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Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) West), 2009-02, Vol.24 (2), p.319-322
Main Authors: Doganis, Dimitrios, Mavrikou, Mersini, Delis, Dimitrios, Stamoyannou, Lela, Siafas, Konstantinos, Sinaniotis, Konstantinos
Format: Article
Language:English
Subjects:
Age
Antibiotics
Care and treatment
Early Diagnosis
Female
Humans
Infant
Infant, Newborn
Infants
Male
Medicine & Public Health
Nephrology
Original Article
Pediatrics
Prevalence
Radiography
Retrospective Studies
Severity of Illness Index
Time Factors
Urinary tract diseases
Urinary tract infections
Urinary Tract Infections - diagnostic imaging
Urinary Tract Infections - epidemiology
Urination
Urine
Urogenital system
Urology
Vesico-Ureteral Reflux - diagnostic imaging
Vesico-Ureteral Reflux - epidemiology
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Summary:The aim of the study was to evaluate whether the timing of performing a voiding cystourethrography (VCUG) following a first urinary tract infection (UTI) in infants is related to the presence or the severity of vesicoureteral reflux (VUR). A total of 411 children (male 230, female 181) with a first-recognised UTI between ages 15 days and 12 months (median 3 months) underwent a VCUG within 4–81 days (median 9 days) following diagnosis. The presence and the grade of the VUR were compared in two groups: an “early” group in which the VCUG was performed during the first week of the start of treatment and a “late” group in which the examination was performed during the second week or thereafter. The prevalence of VUR in the study cohort was 23.3% (96/411 infants). A VUR was diagnosed in 44 infants in the early group (28%) and in 52 in the late group (21%). Reflux of grade III or higher was seen in 25/44 (57%) of the infants in the early group and in 27/52 (52%) infants in the late group. These differences were not significant. Our results suggest that neither the presence nor the grade of VUR in infants is influenced by the timing of the examination following diagnosis. We therefore recommend that it is better to perform VCUG as soon as possible, provided the inflammation has subsided.
ISSN:0931-041X
1432-198X
DOI:10.1007/s00467-008-1018-4