Loading…
Biogenic amine receptors in parasitic nematodes: what can be learned from Caenorhabditis elegans?
The biogenic amines, serotonin, octopamine, tyramine and dopamine regulate many essential processes in parasitic nematodes, such as pharyngeal pumping, muscle contraction, and egg-laying, as well as more complex behaviors, such as mechanosensation and foraging, making biogenic amine receptors excell...
Saved in:
Published in: | Molecular & Biochemical Parasitology 2004-09, Vol.137 (1), p.1-11 |
---|---|
Main Authors: | , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | cdi_FETCH-LOGICAL-c394t-e9275f0e70aa43b0cb7b3027cb1accf18d415a3bcc205ba2421feec7e9826f5c3 |
---|---|
cites | cdi_FETCH-LOGICAL-c394t-e9275f0e70aa43b0cb7b3027cb1accf18d415a3bcc205ba2421feec7e9826f5c3 |
container_end_page | 11 |
container_issue | 1 |
container_start_page | 1 |
container_title | Molecular & Biochemical Parasitology |
container_volume | 137 |
creator | Komuniecki, Richard W. Hobson, Robert J. Rex, Elizabeth B. Hapiak, Vera M. Komuniecki, Patricia R. |
description | The biogenic amines, serotonin, octopamine, tyramine and dopamine regulate many essential processes in parasitic nematodes, such as pharyngeal pumping, muscle contraction, and egg-laying, as well as more complex behaviors, such as mechanosensation and foraging, making biogenic amine receptors excellent targets for drug discovery. This review is designed to summarize our knowledge of nematode biogenic amine signaling and preliminarily identify some of the key receptors involved in the regulation of biogenic amine-dependent behaviors through an analysis of the free-living nematode,
Caenorhabditis elegans. |
doi_str_mv | 10.1016/j.molbiopara.2004.05.010 |
format | article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_66752304</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0166685104001549</els_id><sourcerecordid>66752304</sourcerecordid><originalsourceid>FETCH-LOGICAL-c394t-e9275f0e70aa43b0cb7b3027cb1accf18d415a3bcc205ba2421feec7e9826f5c3</originalsourceid><addsrcrecordid>eNqFkMFu1DAQhi0EokvhFcAnbgljJ7YTLoiuoEWqxAF6tsbOZOtVYi92FsTbk9Wu1COnOcz3_zP6GOMCagFCf9jXc5pcSAfMWEuAtgZVg4BnbCM6I6u-ld1ztllRXelOiSv2qpQ9ACij9Ut2JZQ0fd_qDcObkHYUg-c4h0g8k6fDknLhIfJTfQnLuow045IGKh_5n0dcuMfIHfGJMEca-JjTzLdIMeVHdMMaKZwm2mEsn16zFyNOhd5c5jV7-Prl5_auuv9--237-b7yTd8uFfXSqBHIAGLbOPDOuAak8U6g96PohlYobJz3EpRD2UoxEnlDfSf1qHxzzd6few85_TpSWewciqdpwkjpWKzWRskG2hXszqDPqZRMoz3kMGP-awXYk167t0967UmvBWVXvWv07eXG0c00PAUvPlfg3RkYMVnc5VDsww8JogHoW6XN6frNmaDVxe9A2RYfKHoawup-sUMK___jH9_im9c</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>66752304</pqid></control><display><type>article</type><title>Biogenic amine receptors in parasitic nematodes: what can be learned from Caenorhabditis elegans?</title><source>ScienceDirect Freedom Collection</source><creator>Komuniecki, Richard W. ; Hobson, Robert J. ; Rex, Elizabeth B. ; Hapiak, Vera M. ; Komuniecki, Patricia R.</creator><creatorcontrib>Komuniecki, Richard W. ; Hobson, Robert J. ; Rex, Elizabeth B. ; Hapiak, Vera M. ; Komuniecki, Patricia R.</creatorcontrib><description>The biogenic amines, serotonin, octopamine, tyramine and dopamine regulate many essential processes in parasitic nematodes, such as pharyngeal pumping, muscle contraction, and egg-laying, as well as more complex behaviors, such as mechanosensation and foraging, making biogenic amine receptors excellent targets for drug discovery. This review is designed to summarize our knowledge of nematode biogenic amine signaling and preliminarily identify some of the key receptors involved in the regulation of biogenic amine-dependent behaviors through an analysis of the free-living nematode,
Caenorhabditis elegans.</description><identifier>ISSN: 0166-6851</identifier><identifier>EISSN: 1872-9428</identifier><identifier>DOI: 10.1016/j.molbiopara.2004.05.010</identifier><identifier>PMID: 15279946</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>5-HT ; animal models ; animal parasitic nematodes ; Animals ; Biogenic amine receptors ; biogenic amines ; C. elegans ; Caenorhabditis elegans ; Caenorhabditis elegans - genetics ; Caenorhabditis elegans - physiology ; chemoreceptors ; Dopamine - metabolism ; feeding behavior ; free-living nematodes ; integument ; literature reviews ; Locomotion ; Muscle Contraction ; mutants ; Nematoda - physiology ; Nematode ; Octopamine ; Octopamine - metabolism ; oviposition ; pharyngeal pumping ; pharynx ; Pharynx - physiology ; physiological regulation ; receptor null mutants ; Receptors, Biogenic Amine - genetics ; Receptors, Biogenic Amine - physiology ; Reproduction ; Serotonin - metabolism ; signal transduction ; Tyramine ; Tyramine - metabolism</subject><ispartof>Molecular & Biochemical Parasitology, 2004-09, Vol.137 (1), p.1-11</ispartof><rights>2004</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c394t-e9275f0e70aa43b0cb7b3027cb1accf18d415a3bcc205ba2421feec7e9826f5c3</citedby><cites>FETCH-LOGICAL-c394t-e9275f0e70aa43b0cb7b3027cb1accf18d415a3bcc205ba2421feec7e9826f5c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>313,314,780,784,792,27920,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15279946$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Komuniecki, Richard W.</creatorcontrib><creatorcontrib>Hobson, Robert J.</creatorcontrib><creatorcontrib>Rex, Elizabeth B.</creatorcontrib><creatorcontrib>Hapiak, Vera M.</creatorcontrib><creatorcontrib>Komuniecki, Patricia R.</creatorcontrib><title>Biogenic amine receptors in parasitic nematodes: what can be learned from Caenorhabditis elegans?</title><title>Molecular & Biochemical Parasitology</title><addtitle>Mol Biochem Parasitol</addtitle><description>The biogenic amines, serotonin, octopamine, tyramine and dopamine regulate many essential processes in parasitic nematodes, such as pharyngeal pumping, muscle contraction, and egg-laying, as well as more complex behaviors, such as mechanosensation and foraging, making biogenic amine receptors excellent targets for drug discovery. This review is designed to summarize our knowledge of nematode biogenic amine signaling and preliminarily identify some of the key receptors involved in the regulation of biogenic amine-dependent behaviors through an analysis of the free-living nematode,
Caenorhabditis elegans.</description><subject>5-HT</subject><subject>animal models</subject><subject>animal parasitic nematodes</subject><subject>Animals</subject><subject>Biogenic amine receptors</subject><subject>biogenic amines</subject><subject>C. elegans</subject><subject>Caenorhabditis elegans</subject><subject>Caenorhabditis elegans - genetics</subject><subject>Caenorhabditis elegans - physiology</subject><subject>chemoreceptors</subject><subject>Dopamine - metabolism</subject><subject>feeding behavior</subject><subject>free-living nematodes</subject><subject>integument</subject><subject>literature reviews</subject><subject>Locomotion</subject><subject>Muscle Contraction</subject><subject>mutants</subject><subject>Nematoda - physiology</subject><subject>Nematode</subject><subject>Octopamine</subject><subject>Octopamine - metabolism</subject><subject>oviposition</subject><subject>pharyngeal pumping</subject><subject>pharynx</subject><subject>Pharynx - physiology</subject><subject>physiological regulation</subject><subject>receptor null mutants</subject><subject>Receptors, Biogenic Amine - genetics</subject><subject>Receptors, Biogenic Amine - physiology</subject><subject>Reproduction</subject><subject>Serotonin - metabolism</subject><subject>signal transduction</subject><subject>Tyramine</subject><subject>Tyramine - metabolism</subject><issn>0166-6851</issn><issn>1872-9428</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><recordid>eNqFkMFu1DAQhi0EokvhFcAnbgljJ7YTLoiuoEWqxAF6tsbOZOtVYi92FsTbk9Wu1COnOcz3_zP6GOMCagFCf9jXc5pcSAfMWEuAtgZVg4BnbCM6I6u-ld1ztllRXelOiSv2qpQ9ACij9Ut2JZQ0fd_qDcObkHYUg-c4h0g8k6fDknLhIfJTfQnLuow045IGKh_5n0dcuMfIHfGJMEca-JjTzLdIMeVHdMMaKZwm2mEsn16zFyNOhd5c5jV7-Prl5_auuv9--237-b7yTd8uFfXSqBHIAGLbOPDOuAak8U6g96PohlYobJz3EpRD2UoxEnlDfSf1qHxzzd6few85_TpSWewciqdpwkjpWKzWRskG2hXszqDPqZRMoz3kMGP-awXYk167t0967UmvBWVXvWv07eXG0c00PAUvPlfg3RkYMVnc5VDsww8JogHoW6XN6frNmaDVxe9A2RYfKHoawup-sUMK___jH9_im9c</recordid><startdate>20040901</startdate><enddate>20040901</enddate><creator>Komuniecki, Richard W.</creator><creator>Hobson, Robert J.</creator><creator>Rex, Elizabeth B.</creator><creator>Hapiak, Vera M.</creator><creator>Komuniecki, Patricia R.</creator><general>Elsevier B.V</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040901</creationdate><title>Biogenic amine receptors in parasitic nematodes: what can be learned from Caenorhabditis elegans?</title><author>Komuniecki, Richard W. ; Hobson, Robert J. ; Rex, Elizabeth B. ; Hapiak, Vera M. ; Komuniecki, Patricia R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c394t-e9275f0e70aa43b0cb7b3027cb1accf18d415a3bcc205ba2421feec7e9826f5c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>5-HT</topic><topic>animal models</topic><topic>animal parasitic nematodes</topic><topic>Animals</topic><topic>Biogenic amine receptors</topic><topic>biogenic amines</topic><topic>C. elegans</topic><topic>Caenorhabditis elegans</topic><topic>Caenorhabditis elegans - genetics</topic><topic>Caenorhabditis elegans - physiology</topic><topic>chemoreceptors</topic><topic>Dopamine - metabolism</topic><topic>feeding behavior</topic><topic>free-living nematodes</topic><topic>integument</topic><topic>literature reviews</topic><topic>Locomotion</topic><topic>Muscle Contraction</topic><topic>mutants</topic><topic>Nematoda - physiology</topic><topic>Nematode</topic><topic>Octopamine</topic><topic>Octopamine - metabolism</topic><topic>oviposition</topic><topic>pharyngeal pumping</topic><topic>pharynx</topic><topic>Pharynx - physiology</topic><topic>physiological regulation</topic><topic>receptor null mutants</topic><topic>Receptors, Biogenic Amine - genetics</topic><topic>Receptors, Biogenic Amine - physiology</topic><topic>Reproduction</topic><topic>Serotonin - metabolism</topic><topic>signal transduction</topic><topic>Tyramine</topic><topic>Tyramine - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Komuniecki, Richard W.</creatorcontrib><creatorcontrib>Hobson, Robert J.</creatorcontrib><creatorcontrib>Rex, Elizabeth B.</creatorcontrib><creatorcontrib>Hapiak, Vera M.</creatorcontrib><creatorcontrib>Komuniecki, Patricia R.</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Molecular & Biochemical Parasitology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Komuniecki, Richard W.</au><au>Hobson, Robert J.</au><au>Rex, Elizabeth B.</au><au>Hapiak, Vera M.</au><au>Komuniecki, Patricia R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Biogenic amine receptors in parasitic nematodes: what can be learned from Caenorhabditis elegans?</atitle><jtitle>Molecular & Biochemical Parasitology</jtitle><addtitle>Mol Biochem Parasitol</addtitle><date>2004-09-01</date><risdate>2004</risdate><volume>137</volume><issue>1</issue><spage>1</spage><epage>11</epage><pages>1-11</pages><issn>0166-6851</issn><eissn>1872-9428</eissn><abstract>The biogenic amines, serotonin, octopamine, tyramine and dopamine regulate many essential processes in parasitic nematodes, such as pharyngeal pumping, muscle contraction, and egg-laying, as well as more complex behaviors, such as mechanosensation and foraging, making biogenic amine receptors excellent targets for drug discovery. This review is designed to summarize our knowledge of nematode biogenic amine signaling and preliminarily identify some of the key receptors involved in the regulation of biogenic amine-dependent behaviors through an analysis of the free-living nematode,
Caenorhabditis elegans.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>15279946</pmid><doi>10.1016/j.molbiopara.2004.05.010</doi><tpages>11</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0166-6851 |
ispartof | Molecular & Biochemical Parasitology, 2004-09, Vol.137 (1), p.1-11 |
issn | 0166-6851 1872-9428 |
language | eng |
recordid | cdi_proquest_miscellaneous_66752304 |
source | ScienceDirect Freedom Collection |
subjects | 5-HT animal models animal parasitic nematodes Animals Biogenic amine receptors biogenic amines C. elegans Caenorhabditis elegans Caenorhabditis elegans - genetics Caenorhabditis elegans - physiology chemoreceptors Dopamine - metabolism feeding behavior free-living nematodes integument literature reviews Locomotion Muscle Contraction mutants Nematoda - physiology Nematode Octopamine Octopamine - metabolism oviposition pharyngeal pumping pharynx Pharynx - physiology physiological regulation receptor null mutants Receptors, Biogenic Amine - genetics Receptors, Biogenic Amine - physiology Reproduction Serotonin - metabolism signal transduction Tyramine Tyramine - metabolism |
title | Biogenic amine receptors in parasitic nematodes: what can be learned from Caenorhabditis elegans? |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-14T13%3A10%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Biogenic%20amine%20receptors%20in%20parasitic%20nematodes:%20what%20can%20be%20learned%20from%20Caenorhabditis%20elegans?&rft.jtitle=Molecular%20&%20Biochemical%20Parasitology&rft.au=Komuniecki,%20Richard%20W.&rft.date=2004-09-01&rft.volume=137&rft.issue=1&rft.spage=1&rft.epage=11&rft.pages=1-11&rft.issn=0166-6851&rft.eissn=1872-9428&rft_id=info:doi/10.1016/j.molbiopara.2004.05.010&rft_dat=%3Cproquest_cross%3E66752304%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c394t-e9275f0e70aa43b0cb7b3027cb1accf18d415a3bcc205ba2421feec7e9826f5c3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=66752304&rft_id=info:pmid/15279946&rfr_iscdi=true |