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Patient Survival After Hip Arthroplasty for Metastatic Disease of the Hip

BACKGROUND:The hip joint is a common location for metastatic disease. Actual as well as impending fractures at this site are frequently due to mechanical instability after tumor invasion and are usually treated surgically with hip arthroplasty. The objective of this study was to analyze survival and...

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Published in:Journal of bone and joint surgery. American volume 2004-08, Vol.86 (8), p.1684-1689
Main Authors: Schneiderbauer, Michaela M, von Knoch, Marius, Schleck, Cathy D, Harmsen, William S, Sim, Franklin H, Scully, Sean P
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container_issue 8
container_start_page 1684
container_title Journal of bone and joint surgery. American volume
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creator Schneiderbauer, Michaela M
von Knoch, Marius
Schleck, Cathy D
Harmsen, William S
Sim, Franklin H
Scully, Sean P
description BACKGROUND:The hip joint is a common location for metastatic disease. Actual as well as impending fractures at this site are frequently due to mechanical instability after tumor invasion and are usually treated surgically with hip arthroplasty. The objective of this study was to analyze survival and influences on survival after hip arthroplasty for metastatic hip disease. METHODS:Two hundred and ninety-nine patients who had undergone a total of 306 hemiarthroplasty or total hip arthroplasty procedures for treatment of a pathologic or an impending pathologic hip fracture between 1969 and 1996 at our institution were included in this study. Data that had been acquired prospectively within the total joint registry of our institution were reviewed retrospectively. RESULTS:The median duration of survival after the arthroplasty was 8.6 months. The duration of survival was significantly associated with the site of the fracture, location of the primary tumor, and time from the diagnosis of the primary tumor to the surgery for the fracture (p ≤ 0.05). The time from the diagnosis to the arthroplasty was a significant independent predictor of survival. CONCLUSIONS:Patients undergoing hip arthroplasty for metastatic disease have a limited life expectancy, with only 40% (120) of the 299 patients in our series still alive at one year after the surgery. By identifying prognostic factors regarding life expectancy, this study provides surgeons and oncologists with information with which to weigh risks and benefits of hip arthroplasty for individual patients preoperatively. LEVEL OF EVIDENCE:Prognostic study, Level II-1 (retrospective study). See Instructions to Authors for a complete description of levels of evidence.
doi_str_mv 10.2106/00004623-200408000-00011
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Actual as well as impending fractures at this site are frequently due to mechanical instability after tumor invasion and are usually treated surgically with hip arthroplasty. The objective of this study was to analyze survival and influences on survival after hip arthroplasty for metastatic hip disease. METHODS:Two hundred and ninety-nine patients who had undergone a total of 306 hemiarthroplasty or total hip arthroplasty procedures for treatment of a pathologic or an impending pathologic hip fracture between 1969 and 1996 at our institution were included in this study. Data that had been acquired prospectively within the total joint registry of our institution were reviewed retrospectively. RESULTS:The median duration of survival after the arthroplasty was 8.6 months. The duration of survival was significantly associated with the site of the fracture, location of the primary tumor, and time from the diagnosis of the primary tumor to the surgery for the fracture (p ≤ 0.05). The time from the diagnosis to the arthroplasty was a significant independent predictor of survival. CONCLUSIONS:Patients undergoing hip arthroplasty for metastatic disease have a limited life expectancy, with only 40% (120) of the 299 patients in our series still alive at one year after the surgery. By identifying prognostic factors regarding life expectancy, this study provides surgeons and oncologists with information with which to weigh risks and benefits of hip arthroplasty for individual patients preoperatively. LEVEL OF EVIDENCE:Prognostic study, Level II-1 (retrospective study). See Instructions to Authors for a complete description of levels of evidence.</description><edition>American volume</edition><identifier>ISSN: 0021-9355</identifier><identifier>EISSN: 1535-1386</identifier><identifier>DOI: 10.2106/00004623-200408000-00011</identifier><identifier>PMID: 15292415</identifier><identifier>CODEN: JBJSA3</identifier><language>eng</language><publisher>Boston, MA: Copyright by The Journal of Bone and Joint Surgery, Incorporated</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Arthroplasty, Replacement, Hip ; Biological and medical sciences ; Bone Neoplasms - complications ; Bone Neoplasms - mortality ; Bone Neoplasms - secondary ; Bone Neoplasms - surgery ; Diseases of the osteoarticular system ; Female ; Fractures, Spontaneous - etiology ; Fractures, Spontaneous - mortality ; Fractures, Spontaneous - surgery ; Hip Fractures - etiology ; Hip Fractures - mortality ; Hip Fractures - surgery ; Hip Joint - surgery ; Humans ; Male ; Medical sciences ; Middle Aged ; Retrospective Studies ; Survival Rate ; Time Factors</subject><ispartof>Journal of bone and joint surgery. 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Aug 2004</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4791-509f9a68ff2d991e9e8cbaf3bf1cdae564b6b419f8b75a50f6a6611fdd58b44b3</citedby><cites>FETCH-LOGICAL-c4791-509f9a68ff2d991e9e8cbaf3bf1cdae564b6b419f8b75a50f6a6611fdd58b44b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=15988881$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15292415$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schneiderbauer, Michaela M</creatorcontrib><creatorcontrib>von Knoch, Marius</creatorcontrib><creatorcontrib>Schleck, Cathy D</creatorcontrib><creatorcontrib>Harmsen, William S</creatorcontrib><creatorcontrib>Sim, Franklin H</creatorcontrib><creatorcontrib>Scully, Sean P</creatorcontrib><title>Patient Survival After Hip Arthroplasty for Metastatic Disease of the Hip</title><title>Journal of bone and joint surgery. American volume</title><addtitle>J Bone Joint Surg Am</addtitle><description>BACKGROUND:The hip joint is a common location for metastatic disease. Actual as well as impending fractures at this site are frequently due to mechanical instability after tumor invasion and are usually treated surgically with hip arthroplasty. The objective of this study was to analyze survival and influences on survival after hip arthroplasty for metastatic hip disease. METHODS:Two hundred and ninety-nine patients who had undergone a total of 306 hemiarthroplasty or total hip arthroplasty procedures for treatment of a pathologic or an impending pathologic hip fracture between 1969 and 1996 at our institution were included in this study. Data that had been acquired prospectively within the total joint registry of our institution were reviewed retrospectively. RESULTS:The median duration of survival after the arthroplasty was 8.6 months. The duration of survival was significantly associated with the site of the fracture, location of the primary tumor, and time from the diagnosis of the primary tumor to the surgery for the fracture (p ≤ 0.05). The time from the diagnosis to the arthroplasty was a significant independent predictor of survival. CONCLUSIONS:Patients undergoing hip arthroplasty for metastatic disease have a limited life expectancy, with only 40% (120) of the 299 patients in our series still alive at one year after the surgery. By identifying prognostic factors regarding life expectancy, this study provides surgeons and oncologists with information with which to weigh risks and benefits of hip arthroplasty for individual patients preoperatively. LEVEL OF EVIDENCE:Prognostic study, Level II-1 (retrospective study). 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The time from the diagnosis to the arthroplasty was a significant independent predictor of survival. CONCLUSIONS:Patients undergoing hip arthroplasty for metastatic disease have a limited life expectancy, with only 40% (120) of the 299 patients in our series still alive at one year after the surgery. By identifying prognostic factors regarding life expectancy, this study provides surgeons and oncologists with information with which to weigh risks and benefits of hip arthroplasty for individual patients preoperatively. LEVEL OF EVIDENCE:Prognostic study, Level II-1 (retrospective study). See Instructions to Authors for a complete description of levels of evidence.</abstract><cop>Boston, MA</cop><pub>Copyright by The Journal of Bone and Joint Surgery, Incorporated</pub><pmid>15292415</pmid><doi>10.2106/00004623-200408000-00011</doi><tpages>6</tpages><edition>American volume</edition></addata></record>
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subjects Adult
Aged
Aged, 80 and over
Arthroplasty, Replacement, Hip
Biological and medical sciences
Bone Neoplasms - complications
Bone Neoplasms - mortality
Bone Neoplasms - secondary
Bone Neoplasms - surgery
Diseases of the osteoarticular system
Female
Fractures, Spontaneous - etiology
Fractures, Spontaneous - mortality
Fractures, Spontaneous - surgery
Hip Fractures - etiology
Hip Fractures - mortality
Hip Fractures - surgery
Hip Joint - surgery
Humans
Male
Medical sciences
Middle Aged
Retrospective Studies
Survival Rate
Time Factors
title Patient Survival After Hip Arthroplasty for Metastatic Disease of the Hip
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