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Patient Survival After Hip Arthroplasty for Metastatic Disease of the Hip
BACKGROUND:The hip joint is a common location for metastatic disease. Actual as well as impending fractures at this site are frequently due to mechanical instability after tumor invasion and are usually treated surgically with hip arthroplasty. The objective of this study was to analyze survival and...
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Published in: | Journal of bone and joint surgery. American volume 2004-08, Vol.86 (8), p.1684-1689 |
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container_title | Journal of bone and joint surgery. American volume |
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creator | Schneiderbauer, Michaela M von Knoch, Marius Schleck, Cathy D Harmsen, William S Sim, Franklin H Scully, Sean P |
description | BACKGROUND:The hip joint is a common location for metastatic disease. Actual as well as impending fractures at this site are frequently due to mechanical instability after tumor invasion and are usually treated surgically with hip arthroplasty. The objective of this study was to analyze survival and influences on survival after hip arthroplasty for metastatic hip disease.
METHODS:Two hundred and ninety-nine patients who had undergone a total of 306 hemiarthroplasty or total hip arthroplasty procedures for treatment of a pathologic or an impending pathologic hip fracture between 1969 and 1996 at our institution were included in this study. Data that had been acquired prospectively within the total joint registry of our institution were reviewed retrospectively.
RESULTS:The median duration of survival after the arthroplasty was 8.6 months. The duration of survival was significantly associated with the site of the fracture, location of the primary tumor, and time from the diagnosis of the primary tumor to the surgery for the fracture (p ≤ 0.05). The time from the diagnosis to the arthroplasty was a significant independent predictor of survival.
CONCLUSIONS:Patients undergoing hip arthroplasty for metastatic disease have a limited life expectancy, with only 40% (120) of the 299 patients in our series still alive at one year after the surgery. By identifying prognostic factors regarding life expectancy, this study provides surgeons and oncologists with information with which to weigh risks and benefits of hip arthroplasty for individual patients preoperatively.
LEVEL OF EVIDENCE:Prognostic study, Level II-1 (retrospective study). See Instructions to Authors for a complete description of levels of evidence. |
doi_str_mv | 10.2106/00004623-200408000-00011 |
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METHODS:Two hundred and ninety-nine patients who had undergone a total of 306 hemiarthroplasty or total hip arthroplasty procedures for treatment of a pathologic or an impending pathologic hip fracture between 1969 and 1996 at our institution were included in this study. Data that had been acquired prospectively within the total joint registry of our institution were reviewed retrospectively.
RESULTS:The median duration of survival after the arthroplasty was 8.6 months. The duration of survival was significantly associated with the site of the fracture, location of the primary tumor, and time from the diagnosis of the primary tumor to the surgery for the fracture (p ≤ 0.05). The time from the diagnosis to the arthroplasty was a significant independent predictor of survival.
CONCLUSIONS:Patients undergoing hip arthroplasty for metastatic disease have a limited life expectancy, with only 40% (120) of the 299 patients in our series still alive at one year after the surgery. By identifying prognostic factors regarding life expectancy, this study provides surgeons and oncologists with information with which to weigh risks and benefits of hip arthroplasty for individual patients preoperatively.
LEVEL OF EVIDENCE:Prognostic study, Level II-1 (retrospective study). See Instructions to Authors for a complete description of levels of evidence.</description><edition>American volume</edition><identifier>ISSN: 0021-9355</identifier><identifier>EISSN: 1535-1386</identifier><identifier>DOI: 10.2106/00004623-200408000-00011</identifier><identifier>PMID: 15292415</identifier><identifier>CODEN: JBJSA3</identifier><language>eng</language><publisher>Boston, MA: Copyright by The Journal of Bone and Joint Surgery, Incorporated</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Arthroplasty, Replacement, Hip ; Biological and medical sciences ; Bone Neoplasms - complications ; Bone Neoplasms - mortality ; Bone Neoplasms - secondary ; Bone Neoplasms - surgery ; Diseases of the osteoarticular system ; Female ; Fractures, Spontaneous - etiology ; Fractures, Spontaneous - mortality ; Fractures, Spontaneous - surgery ; Hip Fractures - etiology ; Hip Fractures - mortality ; Hip Fractures - surgery ; Hip Joint - surgery ; Humans ; Male ; Medical sciences ; Middle Aged ; Retrospective Studies ; Survival Rate ; Time Factors</subject><ispartof>Journal of bone and joint surgery. American volume, 2004-08, Vol.86 (8), p.1684-1689</ispartof><rights>Copyright 2004 by The Journal of Bone and Joint Surgery, Incorporated</rights><rights>2004 INIST-CNRS</rights><rights>Copyright Journal of Bone and Joint Surgery, Inc. Aug 2004</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4791-509f9a68ff2d991e9e8cbaf3bf1cdae564b6b419f8b75a50f6a6611fdd58b44b3</citedby><cites>FETCH-LOGICAL-c4791-509f9a68ff2d991e9e8cbaf3bf1cdae564b6b419f8b75a50f6a6611fdd58b44b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15988881$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15292415$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schneiderbauer, Michaela M</creatorcontrib><creatorcontrib>von Knoch, Marius</creatorcontrib><creatorcontrib>Schleck, Cathy D</creatorcontrib><creatorcontrib>Harmsen, William S</creatorcontrib><creatorcontrib>Sim, Franklin H</creatorcontrib><creatorcontrib>Scully, Sean P</creatorcontrib><title>Patient Survival After Hip Arthroplasty for Metastatic Disease of the Hip</title><title>Journal of bone and joint surgery. American volume</title><addtitle>J Bone Joint Surg Am</addtitle><description>BACKGROUND:The hip joint is a common location for metastatic disease. Actual as well as impending fractures at this site are frequently due to mechanical instability after tumor invasion and are usually treated surgically with hip arthroplasty. The objective of this study was to analyze survival and influences on survival after hip arthroplasty for metastatic hip disease.
METHODS:Two hundred and ninety-nine patients who had undergone a total of 306 hemiarthroplasty or total hip arthroplasty procedures for treatment of a pathologic or an impending pathologic hip fracture between 1969 and 1996 at our institution were included in this study. Data that had been acquired prospectively within the total joint registry of our institution were reviewed retrospectively.
RESULTS:The median duration of survival after the arthroplasty was 8.6 months. The duration of survival was significantly associated with the site of the fracture, location of the primary tumor, and time from the diagnosis of the primary tumor to the surgery for the fracture (p ≤ 0.05). The time from the diagnosis to the arthroplasty was a significant independent predictor of survival.
CONCLUSIONS:Patients undergoing hip arthroplasty for metastatic disease have a limited life expectancy, with only 40% (120) of the 299 patients in our series still alive at one year after the surgery. By identifying prognostic factors regarding life expectancy, this study provides surgeons and oncologists with information with which to weigh risks and benefits of hip arthroplasty for individual patients preoperatively.
LEVEL OF EVIDENCE:Prognostic study, Level II-1 (retrospective study). See Instructions to Authors for a complete description of levels of evidence.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Arthroplasty, Replacement, Hip</subject><subject>Biological and medical sciences</subject><subject>Bone Neoplasms - complications</subject><subject>Bone Neoplasms - mortality</subject><subject>Bone Neoplasms - secondary</subject><subject>Bone Neoplasms - surgery</subject><subject>Diseases of the osteoarticular system</subject><subject>Female</subject><subject>Fractures, Spontaneous - etiology</subject><subject>Fractures, Spontaneous - mortality</subject><subject>Fractures, Spontaneous - surgery</subject><subject>Hip Fractures - etiology</subject><subject>Hip Fractures - mortality</subject><subject>Hip Fractures - surgery</subject><subject>Hip Joint - surgery</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Survival Rate</subject><subject>Time Factors</subject><issn>0021-9355</issn><issn>1535-1386</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><recordid>eNp1kdtKAzEQhoMoWquvIEHQu9Vkc9jNZfFYUBTU65DdndCtabcmWcW3N7X1gOBAmAS-fxi-IIQpOckpkackFZc5y_LUSZleWTqUbqABFUxklJVyEw0IyWmmmBA7aDeE6TLESbGNdqjIVc6pGKDxvYktzCN-6P1r-2ocHtkIHl-3CzzyceK7hTMhvmPbeXwLMd1ToMbnbQATAHcWxwks8T20ZY0LsL_uQ_R0efF4dp3d3F2Nz0Y3Wc0LRTNBlFVGltbmjVIUFJR1ZSyrLK0bA0LySlacKltWhTCCWGmkpNQ2jSgrzis2RMeruQvfvfQQop61oQbnzBy6PmgpC8FYkjNEh3_Aadf7edpN50SQgnFCElSuoNp3IXiweuHbmfHvmhK9dK2_XOtv1_rTdYoerOf31Qyan-BabgKO1oAJtXHWm3ndhl-cKlMtB_EV99a55D48u_4NvJ6AcXGi__tr9gGUV5T0</recordid><startdate>200408</startdate><enddate>200408</enddate><creator>Schneiderbauer, Michaela M</creator><creator>von Knoch, Marius</creator><creator>Schleck, Cathy D</creator><creator>Harmsen, William S</creator><creator>Sim, Franklin H</creator><creator>Scully, Sean P</creator><general>Copyright by The Journal of Bone and Joint Surgery, Incorporated</general><general>Journal of Bone and Joint Surgery Incorporated</general><general>Journal of Bone and Joint Surgery AMERICAN VOLUME</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7QO</scope><scope>7QP</scope><scope>7RV</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7N</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>200408</creationdate><title>Patient Survival After Hip Arthroplasty for Metastatic Disease of the Hip</title><author>Schneiderbauer, Michaela M ; von Knoch, Marius ; Schleck, Cathy D ; Harmsen, William S ; Sim, Franklin H ; Scully, Sean P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4791-509f9a68ff2d991e9e8cbaf3bf1cdae564b6b419f8b75a50f6a6611fdd58b44b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Arthroplasty, Replacement, Hip</topic><topic>Biological and medical sciences</topic><topic>Bone Neoplasms - complications</topic><topic>Bone Neoplasms - mortality</topic><topic>Bone Neoplasms - secondary</topic><topic>Bone Neoplasms - surgery</topic><topic>Diseases of the osteoarticular system</topic><topic>Female</topic><topic>Fractures, Spontaneous - etiology</topic><topic>Fractures, Spontaneous - mortality</topic><topic>Fractures, Spontaneous - surgery</topic><topic>Hip Fractures - etiology</topic><topic>Hip Fractures - mortality</topic><topic>Hip Fractures - surgery</topic><topic>Hip Joint - surgery</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>Survival Rate</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schneiderbauer, Michaela M</creatorcontrib><creatorcontrib>von Knoch, Marius</creatorcontrib><creatorcontrib>Schleck, Cathy D</creatorcontrib><creatorcontrib>Harmsen, William S</creatorcontrib><creatorcontrib>Sim, Franklin H</creatorcontrib><creatorcontrib>Scully, Sean P</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of bone and joint surgery. American volume</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schneiderbauer, Michaela M</au><au>von Knoch, Marius</au><au>Schleck, Cathy D</au><au>Harmsen, William S</au><au>Sim, Franklin H</au><au>Scully, Sean P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Patient Survival After Hip Arthroplasty for Metastatic Disease of the Hip</atitle><jtitle>Journal of bone and joint surgery. American volume</jtitle><addtitle>J Bone Joint Surg Am</addtitle><date>2004-08</date><risdate>2004</risdate><volume>86</volume><issue>8</issue><spage>1684</spage><epage>1689</epage><pages>1684-1689</pages><issn>0021-9355</issn><eissn>1535-1386</eissn><coden>JBJSA3</coden><abstract>BACKGROUND:The hip joint is a common location for metastatic disease. Actual as well as impending fractures at this site are frequently due to mechanical instability after tumor invasion and are usually treated surgically with hip arthroplasty. The objective of this study was to analyze survival and influences on survival after hip arthroplasty for metastatic hip disease.
METHODS:Two hundred and ninety-nine patients who had undergone a total of 306 hemiarthroplasty or total hip arthroplasty procedures for treatment of a pathologic or an impending pathologic hip fracture between 1969 and 1996 at our institution were included in this study. Data that had been acquired prospectively within the total joint registry of our institution were reviewed retrospectively.
RESULTS:The median duration of survival after the arthroplasty was 8.6 months. The duration of survival was significantly associated with the site of the fracture, location of the primary tumor, and time from the diagnosis of the primary tumor to the surgery for the fracture (p ≤ 0.05). The time from the diagnosis to the arthroplasty was a significant independent predictor of survival.
CONCLUSIONS:Patients undergoing hip arthroplasty for metastatic disease have a limited life expectancy, with only 40% (120) of the 299 patients in our series still alive at one year after the surgery. By identifying prognostic factors regarding life expectancy, this study provides surgeons and oncologists with information with which to weigh risks and benefits of hip arthroplasty for individual patients preoperatively.
LEVEL OF EVIDENCE:Prognostic study, Level II-1 (retrospective study). See Instructions to Authors for a complete description of levels of evidence.</abstract><cop>Boston, MA</cop><pub>Copyright by The Journal of Bone and Joint Surgery, Incorporated</pub><pmid>15292415</pmid><doi>10.2106/00004623-200408000-00011</doi><tpages>6</tpages><edition>American volume</edition></addata></record> |
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subjects | Adult Aged Aged, 80 and over Arthroplasty, Replacement, Hip Biological and medical sciences Bone Neoplasms - complications Bone Neoplasms - mortality Bone Neoplasms - secondary Bone Neoplasms - surgery Diseases of the osteoarticular system Female Fractures, Spontaneous - etiology Fractures, Spontaneous - mortality Fractures, Spontaneous - surgery Hip Fractures - etiology Hip Fractures - mortality Hip Fractures - surgery Hip Joint - surgery Humans Male Medical sciences Middle Aged Retrospective Studies Survival Rate Time Factors |
title | Patient Survival After Hip Arthroplasty for Metastatic Disease of the Hip |
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