Syncope: facts and fiction

According to the current state-of-art on the brainstem functional anatomy and reticular formation, authors believe that nucleus tractus solitarii (NTS) is the neural structure, which meets all the conditions of the hypothetical syncope generating, reflex centre. The afferent branch of this reflex ar...

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Published in:Medical hypotheses 2004, Vol.63 (3), p.394-401
Main Authors: Zurak, Niko, Bilic, Ervina
Format: Article
Language:English
Subjects:
Afferent Pathways - physiopathology
Cerebral Cortex - physiopathology
Feedback
Humans
Models, Neurological
Nerve Net - physiopathology
Reflex
Reticular Formation - physiopathology
Solitary Nucleus - physiopathology
Syncope - physiopathology
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description According to the current state-of-art on the brainstem functional anatomy and reticular formation, authors believe that nucleus tractus solitarii (NTS) is the neural structure, which meets all the conditions of the hypothetical syncope generating, reflex centre. The afferent branch of this reflex arc represents information from different visceral sources including the brain itself. The efferent branch of this reflex arc is reticular activating system (RAS). The executive mechanism of syncope is deactivation of RAS done with the active engagement of NTS through solitarioreticular pathway (SRT) and parabrachial nuclear complex (PBC). The biological purpose of syncope would be resetting of the NTS in case of an unbearable vegetative input, which is code for triggering the mechanism described.
doi_str_mv 10.1016/j.mehy.2004.02.045
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subjects Afferent Pathways - physiopathology
Cerebral Cortex - physiopathology
Feedback
Humans
Models, Neurological
Nerve Net - physiopathology
Reflex
Reticular Formation - physiopathology
Solitary Nucleus - physiopathology
Syncope - physiopathology
title Syncope: facts and fiction
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