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Differential diagnosis of optic neuritis in a patient with ankylosing spondylitis
The authors report a 38-year-old white man with ankylosing spondylitis (AS) who presented with recurrent ischaemic optic neuritis. The initial diagnosis was of multiple sclerosis, but further investigation showed serology and cerebrospinal fluid culture positive for syphilis. After treatment for ter...
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Published in: | Rheumatology international 2004-07, Vol.24 (4), p.247-249 |
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container_title | Rheumatology international |
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creator | APPENZELLER, Simone WERNER DE CASTRO, Glaucio R SAMPAIO-BARROS, Percival D SACHETTO, Zoraida SAMARA, Adil M FERNANDES, Sandra Regina M |
description | The authors report a 38-year-old white man with ankylosing spondylitis (AS) who presented with recurrent ischaemic optic neuritis. The initial diagnosis was of multiple sclerosis, but further investigation showed serology and cerebrospinal fluid culture positive for syphilis. After treatment for tertiary syphilis with penicillin, there was complete remission of the ocular symptoms. This case illustrates the differential diagnosis of optic neuritis in AS and supports the relevance of investigating infectious diseases in the management of ischaemic optic neuritis. |
doi_str_mv | 10.1007/s00296-003-0401-5 |
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subjects | Adult Biological and medical sciences Diagnosis, Differential Diseases of the osteoarticular system Diseases of visual field, optic nerve, optic chiasma and optic tracts Humans Inflammatory joint diseases Male Medical sciences Multiple sclerosis Multiple Sclerosis - diagnosis Ophthalmology Optic nerve Optic Neuritis - diagnosis Optic Neuritis - etiology Penicillins - therapeutic use Spondylitis, Ankylosing - complications Spondylitis, Ankylosing - diagnosis Syphilis - drug therapy Syphilis - immunology Syphilis - pathology Syphilis Serodiagnosis Treatment Outcome |
title | Differential diagnosis of optic neuritis in a patient with ankylosing spondylitis |
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