Hypopituitarism presenting as a mixed hyperlipidaemia

A case report is presented of a 37-year-old man who, largely by chance, was found to have a marked mixed hyperlipidaemia. As a teenager he had been treated for apparent idiopathic growth hormone deficiency, but had also never developed secondary sexual characteristics. Pituitary hormone measurement...

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Bibliographic Details
Published in:Annals of clinical biochemistry 2004-07, Vol.41 (4), p.344-345
Main Authors: Kilpatrick, Eric S, Patmore, Jane E, Rowland-Hill, Christopher, Atkin, Stephen L
Format: Article
Language:English
Subjects:
Adult
Humans
Hydrocortisone - therapeutic use
Hyperlipidemias - diagnosis
Hyperlipidemias - etiology
Hypopituitarism - blood
Hypopituitarism - complications
Hypopituitarism - diagnosis
Hypopituitarism - drug therapy
Magnetic Resonance Imaging
Male
Pituitary Gland - pathology
Pituitary Hormones - blood
Testosterone - therapeutic use
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Summary:A case report is presented of a 37-year-old man who, largely by chance, was found to have a marked mixed hyperlipidaemia. As a teenager he had been treated for apparent idiopathic growth hormone deficiency, but had also never developed secondary sexual characteristics. Pituitary hormone measurement was now consistent with hypopituitarism and magnetic resonance imaging showed hypoplasia of his pituitary stalk as the likely cause. His hyperlipidaemia improved after appropriate hormone replacement. He thus appears to have had a mixed hyperlipidaemia secondary to hypopituitarism, which was secondary to a pituitary stalk abnormality, which in turn may have been associated to the trauma surrounding his normal breech delivery.
ISSN:0004-5632
1758-1001
DOI:10.1258/0004563041201581