Pyridylthiocarbazide complexes of rhenium with potential radiopharmaceutical applications

Attachment of a thioamide tethering group provides a modification of the well-known pyridylhydrazine based route to radiolabelling of biomolecules (the HYNIC system) and gives a proligand which gives stable, well-defined chelated derivatives with both Re(v) oxo and Re(III) diazenide cores. Both disp...

Full description

Saved in:
Bibliographic Details
Published in:Dalton transactions : an international journal of inorganic chemistry 2004-08 (16), p.2402-2403
Main Authors: Clarke, Carole, Cowley, Andrew R, Dilworth, Jonathan R, Donnelly, Paul S
Format: Article
Language:English
Subjects:
Crystallography, X-Ray
Hydrazines - chemistry
Indicators and Reagents
Isotope Labeling
Models, Molecular
Radioisotopes
Radiopharmaceuticals - chemical synthesis
Radiopharmaceuticals - chemistry
Rhenium - chemistry
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Attachment of a thioamide tethering group provides a modification of the well-known pyridylhydrazine based route to radiolabelling of biomolecules (the HYNIC system) and gives a proligand which gives stable, well-defined chelated derivatives with both Re(v) oxo and Re(III) diazenide cores. Both display previously unknown bonding modes for the pyridylthiocarbazide ligands.
ISSN:1477-9226
1477-9234
DOI:10.1039/B406439A