Acute transplant rejection induced by blood transfusion reaction to the Kidd blood group system

Many renal transplant centres now try to avoid blood transfusion prior to renal transplantation, to avoid alloimmunization due to antibody production against donor antigens usually present on contaminating white cells. Post- or peri-operative transfusions are usually not considered to present proble...

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Bibliographic Details
Published in:Nephrology, dialysis, transplantation dialysis, transplantation, 2004-09, Vol.19 (9), p.2403-2406
Main Authors: Holt, Stephen, Donaldson, Helen, Hazlehurst, Geoffrey, Varghese, Zac, Contreras, Marcela, Kingdon, Edward, Sweny, Paul, Burns, Aine
Format: Article
Language:English
Subjects:
Acute Disease
Adult
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
blood transfusion
Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis
Emergency and intensive care: renal failure. Dialysis management
Female
Graft Rejection - blood
Humans
Intensive care medicine
Kidd blood group antigens
Kidd Blood-Group System
Kidney Transplantation - adverse effects
Living Donors
Medical sciences
rejection
renal transplantation
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the urinary system
Transfusion Reaction
Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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Summary:Many renal transplant centres now try to avoid blood transfusion prior to renal transplantation, to avoid alloimmunization due to antibody production against donor antigens usually present on contaminating white cells. Post- or peri-operative transfusions are usually not considered to present problems, since the patient is heavily immunosuppressed. We present a patient who suffered a rare transfusion reaction, that we believe may have initiated a severe vascular rejection of a kidney transplant, probably mediated by Kidd blood group antigens.
ISSN:0931-0509
1460-2385
DOI:10.1093/ndt/gfh333