Paraneoplastic Hypertension Associated With Renal Oncocytoma: Management With Cryoablation

Paraneoplastic hypertension associated with a renal oncocytoma is an unreported syndrome. We report a unique case of a patient with multidrug-resistant hypertension who was found to have a solitary renal mass. Cryoablation was performed and resulted in an immediate and dramatic decrease in blood pre...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2009, Vol.73 (1), p.209.e9-209.e11
Main Authors: Jayaratna, Isuru, Munver, Ravi, Disick, Grant, Han, Min W, Sawczuk, Ihor
Format: Article
Language:English
Subjects:
Adenoma, Oxyphilic - complications
Adenoma, Oxyphilic - surgery
Cryosurgery
Humans
Hypertension - etiology
Hypertension - surgery
Kidney Neoplasms - complications
Kidney Neoplasms - surgery
Male
Middle Aged
Paraneoplastic Syndromes - etiology
Paraneoplastic Syndromes - surgery
Urology
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Summary:Paraneoplastic hypertension associated with a renal oncocytoma is an unreported syndrome. We report a unique case of a patient with multidrug-resistant hypertension who was found to have a solitary renal mass. Cryoablation was performed and resulted in an immediate and dramatic decrease in blood pressure. Histologic review of intraoperative biopsy specimens revealed findings consistent with renal oncocytoma. To our knowledge, this is the first report of hypertension in the setting of a renal oncocytoma, with subsequent improvement of this paraneoplastic syndrome after cryoablation.
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2008.02.011