Analysis of auditory evoked potential parameters in the presence of radiofrequency fields using a support vector machines method

• Published in: Medical & biological engineering & computing 2004-07, Vol.42 (4), p.562-568
• Main Authors: Maby, E, Le Bouquin Jeannès, R, Liégeois-Chauvel, C, Gourevitch, B, Faucon, G
• Format: Article
• Language: English
• Subjects: Biomedical engineering; Cell Phone; Electroencephalography - methods; Electromagnetic Fields; Epilepsy; Epilepsy, Temporal Lobe - physiopathology; Evoked Potentials, Auditory; Humans; Radio frequency; Signal Processing, Computer-Assisted; Studies; Support vector machines
• ISSN: 0140-0118; 1741-0444
• DOI: 10.1007/BF02351000

The paper presents a study of global system for mobile (GSM) phone radiofrequency effects on human cerebral activity. The work was based on the study of auditory evoked potentials (AEPs) recorded from healthy humans and epileptic patients. The protocol allowed the comparison of AEPs recorded with or without exposure to electrical fields. Ten variables measured from AEPs were employed in the design of a supervised support vector machines classifier. The classification performance measured the classifier's ability to discriminate features performed with or without radiofrequency exposure. Most significant features were chosen by a backward sequential selection that ranked the variables according to their pertinence for the discrimination. Finally, the most discriminating features were analysed statistically by a Wilcoxon signed rank test. For both populations, the N100 amplitudes were reduced under the influence of GSM radiofrequency (mean attenuation of -0.36 microV for healthy subjects and -0.60 microV for epileptic patients). Healthy subjects showed a N100 latency decrease (-5.23 ms in mean), which could be consistent with mild, localised heating. The auditory cortical activity in humans was modified by GSM phone radiofrequencies, but an effect on brain functionality has not been proven.