Transient TTP in childhood

Thrombotic thrombocytopenic purpura (TTP) is a type of microangiopathic hemolytic anemia that is uncommon in childhood. Adults with TTP have a high mortality rate unless they are treated with plasma exchange. There are few reports of children with acquired idiopathic TTP, and most of those children...

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Bibliographic Details
Published in:Pediatric blood & cancer 2009-03, Vol.52 (3), p.424-426
Main Authors: Moskowitz, Naomi P., Fligman, Igal, Scimeca, Philip, Weinblatt, Mark
Format: Article
Language:English
Subjects:
anemia
Child, Preschool
childhood
Female
Hemoglobins - metabolism
Humans
Platelet Count
Purpura, Thrombotic Thrombocytopenic - blood
Purpura, Thrombotic Thrombocytopenic - pathology
thrombocytopenia
Time Factors
TTP
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Summary:Thrombotic thrombocytopenic purpura (TTP) is a type of microangiopathic hemolytic anemia that is uncommon in childhood. Adults with TTP have a high mortality rate unless they are treated with plasma exchange. There are few reports of children with acquired idiopathic TTP, and most of those children received some form of treatment. We describe a child with acquired idiopathic TTP who had severe thrombocytopenia and anemia that resolved over several months without the use of any medications. This case suggests that some children with acquired idiopathic TTP might be safely observed without ill effects. Pediatr Blood Cancer 2009;52:424–426. © 2008 Wiley‐Liss, Inc.
ISSN:1545-5009
1545-5017
DOI:10.1002/pbc.21818