Multicentric granular cell tumor: report of a patient with oral and cutaneous lesions

Abstract Granular cell tumor (GCT) is an uncommon benign neoplasm of soft tissue that characteristically affects the oral cavity, with increased frequency in the tongue. In this paper, we report a multicentric GCT affecting a 41-year-old black woman, with nodules in perineum, groin, vulva, tongue an...

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Published in:British journal of oral & maxillofacial surgery 2009-01, Vol.47 (1), p.62-64
Main Authors: Sargenti-Neto, Sergio, Brazão–Silva, Marco Túllio, do Nascimento Souza, Kelen Christine, de Faria, Paulo Rogério, Durighetto-Júnior, Antônio Francisco, Loyola, Adriano Mota, Cardoso, Sérgio Vitorino
Format: Article
Language:English
Subjects:
Abrikossof’s tumor
Adult
Biological and medical sciences
Dentistry
Female
Genital Neoplasms, Female - surgery
Granular cell myoblastoma
Granular cell tumor
Granular Cell Tumor - pathology
Humans
Lip Neoplasms - pathology
Medical sciences
Multiple Primary Neoplasms
Neoplasm recurrence
Neoplasm Recurrence, Local
Neoplasms, Multiple Primary - pathology
Otorhinolaryngology. Stomatology
Perineum - pathology
Perineum - surgery
Skin Neoplasms - pathology
Surgery
Tongue Neoplasms - pathology
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Summary:Abstract Granular cell tumor (GCT) is an uncommon benign neoplasm of soft tissue that characteristically affects the oral cavity, with increased frequency in the tongue. In this paper, we report a multicentric GCT affecting a 41-year-old black woman, with nodules in perineum, groin, vulva, tongue and lip. Some of these lesions were surgically resected, but in a six-year follow-up, new primary lesions and recurrences were observed. In addition, the patient opted to do not remove some of these lesions, but there were not significant intercurrences. In view of the present findings, aspects related to clinical presentation, multiplicity, malignant potential, and treatment of GCT are discussed.
ISSN:0266-4356
1532-1940
DOI:10.1016/j.bjoms.2008.06.015