Effect of simvastatin on endothelial function in cardiac syndrome X patients

Patients with cardiac syndrome X with mild hypercholesterolemia were randomized to placebo (n = 20) or simvastatin 20 mg/day (n = 20). In the simvastatin group, there was a significant (26%; p

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Bibliographic Details
Published in:The American journal of cardiology 2004-09, Vol.94 (5), p.652-655
Main Authors: Fábián, Emília, Varga, Albert, Picano, Eugenio, Vajo, Zoltan, Rónaszéki, Aladár, Csanády, Miklós
Format: Article
Language:English
Subjects:
Aged
Anticholesteremic Agents - pharmacology
Anticholesteremic Agents - therapeutic use
Biological and medical sciences
Cardiology
Cardiovascular disease
Circulatory system
Drug therapy
Endothelium, Vascular - drug effects
Endothelium, Vascular - physiopathology
Exercise - physiology
Female
Humans
Hypercholesterolemia - complications
Hypercholesterolemia - drug therapy
Male
Medical sciences
Metabolic diseases
Microvascular Angina - complications
Microvascular Angina - drug therapy
Middle Aged
Miscellaneous
Myocardial Ischemia - complications
Myocardial Ischemia - drug therapy
Other metabolic disorders
Simvastatin - pharmacology
Simvastatin - therapeutic use
Treatment Outcome
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Description
Summary:Patients with cardiac syndrome X with mild hypercholesterolemia were randomized to placebo (n = 20) or simvastatin 20 mg/day (n = 20). In the simvastatin group, there was a significant (26%; p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2004.05.035