Intracranial Fusariosis: A Novel Cause of Fungal Meningoencephalitis in a Dog

The Fusarium species are a group of saprophytic fungal organisms that are occasionally the cause of opportunistic infections in humans and animals. Central nervous system disease associated with a Fusarium species is most commonly described in horse, resulting in equine leukoencephalomalacia. This r...

Full description

Saved in:
Bibliographic Details
Published in:Veterinary pathology 2004-09, Vol.41 (5), p.510-514
Main Authors: Evans, J., Levesque, D., de Lahunta, A., Jensen, H. E.
Format: Article
Language:English
Subjects:
Animals
Brain - diagnostic imaging
Dog Diseases - microbiology
Dog Diseases - pathology
Dogs
Fatal Outcome
Female
Fusarium
Immunohistochemistry - veterinary
Meningoencephalitis - microbiology
Meningoencephalitis - pathology
Meningoencephalitis - veterinary
Mycoses - pathology
Mycoses - veterinary
Tomography, X-Ray Computed - veterinary
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The Fusarium species are a group of saprophytic fungal organisms that are occasionally the cause of opportunistic infections in humans and animals. Central nervous system disease associated with a Fusarium species is most commonly described in horse, resulting in equine leukoencephalomalacia. This report describes a 2-year-old, spayed, female German Shepherd Dog with meningoencephalitis secondary to infection with Fusarium spp. Meningoencephalitis in dogs secondary to a species of Fusarium has not been previously reported. The diagnosis was made based on the histopathologic examination of brain tissues postmortem and special immunohistochemical stains specific for Fusarium solani. The clinical signs in this dog were indicative of multifocal brain disease and included seizures and a paradoxical vestibular syndrome. The clinical findings, diagnostic and histopathologic test results, and the comparative characterizations of other disseminated fungal diseases, especially aspergillosis, are described.
ISSN:0300-9858
1544-2217
DOI:10.1354/vp.41-5-510