Prevalence and Progression of Subclinical Atherosclerosis in Younger Adults With Low Short-Term but High Lifetime Estimated Risk For Cardiovascular Disease : The Coronary Artery Risk Development in Young Adults Study and Multi-Ethnic Study of Atherosclerosis

We hypothesized that individuals with low 10-year but high lifetime cardiovascular disease risk would have a greater burden of subclinical atherosclerosis than those with low 10-year but low lifetime risk. We included 2988 individuals < or = 50 years of age at examination year 15 from the Coronar...

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Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 2009-01, Vol.119 (3), p.382-389
Main Authors: BERRY, Jarett D, LIU, Kiang, LLOYD-JONES, Donald M, FOLSOM, Aaron R, LEWIS, Cora E, CARR, J. Jeffrey, POLAK, Joseph F, SHEA, Steven, SIDNEY, Stephen, O'LEARY, Daniel H, CHAN, Cheeling
Format: Article
Language:English
Subjects:
Adult
Age Factors
Atherosclerosis (general aspects, experimental research)
Atherosclerosis - epidemiology
Atherosclerosis - ethnology
Atherosclerosis - pathology
Biological and medical sciences
Blood and lymphatic vessels
Cardiology. Vascular system
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - ethnology
Cardiovascular Diseases - pathology
Coronary Artery Disease - ethnology
Coronary Artery Disease - pathology
Disease Progression
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Ethnic Groups - ethnology
Female
Humans
Hypercholesterolemia - complications
Hypercholesterolemia - ethnology
Hypercholesterolemia - pathology
Hypertension - complications
Hypertension - ethnology
Hypertension - pathology
Longitudinal Studies
Male
Medical sciences
Middle Aged
Prevalence
Risk Factors
Smoking - adverse effects
Smoking - ethnology
Smoking - pathology
Time Factors
Citations: Items that this one cites
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Summary:We hypothesized that individuals with low 10-year but high lifetime cardiovascular disease risk would have a greater burden of subclinical atherosclerosis than those with low 10-year but low lifetime risk. We included 2988 individuals < or = 50 years of age at examination year 15 from the Coronary Artery Risk Development in Young Adults (CARDIA) study and 1076 individuals < or = 50 of age at study entry from the Multi-Ethnic Study of Atherosclerosis (MESA). The 10-year risk and lifetime risk for cardiovascular disease were estimated for each participant, permitting stratification into 3 groups: low 10-year (
ISSN:0009-7322
1524-4539
DOI:10.1161/CIRCULATIONAHA.108.800235