Primary lung large cell carcinoma metastatic to the vulva: a case report and review of the literature

Background. Metastatic cancer to the vulva is a rare diagnosis and is estimated to account for 5–8% of all vulvar cancers. Case. A 57-year-old postmenopausal woman was referred for the evaluation of a new vulvar mass. CT scan of the pelvis demonstrated a 4 × 6 cm lobular mass of the left labia. An o...

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Bibliographic Details
Published in:Gynecologic oncology 2004-09, Vol.94 (3), p.829-831
Main Authors: Rocconi, Rodney P., Leath, Charles A., Johnson, William M., Barnes, Mack N., Conner, Michael G.
Format: Article
Language:English
Subjects:
Carcinoma, Large Cell - pathology
Carcinoma, Large Cell - secondary
Female
Humans
Lung Neoplasms - pathology
Metastatic lung carcinoma
Middle Aged
Vulvar lesions
Vulvar Neoplasms - pathology
Vulvar Neoplasms - secondary
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Summary:Background. Metastatic cancer to the vulva is a rare diagnosis and is estimated to account for 5–8% of all vulvar cancers. Case. A 57-year-old postmenopausal woman was referred for the evaluation of a new vulvar mass. CT scan of the pelvis demonstrated a 4 × 6 cm lobular mass of the left labia. An outpatient excisional biopsy revealed a poorly differentiated large cell carcinoma with prominent necrosis and focal perineural invasion consistent with a bronchogenic carcinoma. A subsequent PET scan of the chest revealed a large primary lung carcinoma confirmed by CT-guided biopsy that was identical to the vulvar tumor. Conclusion. This case represents the only literature described primary lung carcinoma presenting as a vulvar metastasis.
ISSN:0090-8258
1095-6859
DOI:10.1016/j.ygyno.2004.06.006