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Primary lung large cell carcinoma metastatic to the vulva: a case report and review of the literature

Background. Metastatic cancer to the vulva is a rare diagnosis and is estimated to account for 5–8% of all vulvar cancers. Case. A 57-year-old postmenopausal woman was referred for the evaluation of a new vulvar mass. CT scan of the pelvis demonstrated a 4 × 6 cm lobular mass of the left labia. An o...

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Published in:	Gynecologic oncology 2004-09, Vol.94 (3), p.829-831
Main Authors:	Rocconi, Rodney P., Leath, Charles A., Johnson, William M., Barnes, Mack N., Conner, Michael G.
Format:	Article
Language:	English
Subjects:	Carcinoma, Large Cell - pathology Carcinoma, Large Cell - secondary Female Humans Lung Neoplasms - pathology Metastatic lung carcinoma Middle Aged Vulvar lesions Vulvar Neoplasms - pathology Vulvar Neoplasms - secondary
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container_title	Gynecologic oncology
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creator	Rocconi, Rodney P. Leath, Charles A. Johnson, William M. Barnes, Mack N. Conner, Michael G.
description	Background. Metastatic cancer to the vulva is a rare diagnosis and is estimated to account for 5–8% of all vulvar cancers. Case. A 57-year-old postmenopausal woman was referred for the evaluation of a new vulvar mass. CT scan of the pelvis demonstrated a 4 × 6 cm lobular mass of the left labia. An outpatient excisional biopsy revealed a poorly differentiated large cell carcinoma with prominent necrosis and focal perineural invasion consistent with a bronchogenic carcinoma. A subsequent PET scan of the chest revealed a large primary lung carcinoma confirmed by CT-guided biopsy that was identical to the vulvar tumor. Conclusion. This case represents the only literature described primary lung carcinoma presenting as a vulvar metastasis.
doi_str_mv	10.1016/j.ygyno.2004.06.006
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Metastatic cancer to the vulva is a rare diagnosis and is estimated to account for 5–8% of all vulvar cancers. Case. A 57-year-old postmenopausal woman was referred for the evaluation of a new vulvar mass. CT scan of the pelvis demonstrated a 4 × 6 cm lobular mass of the left labia. An outpatient excisional biopsy revealed a poorly differentiated large cell carcinoma with prominent necrosis and focal perineural invasion consistent with a bronchogenic carcinoma. A subsequent PET scan of the chest revealed a large primary lung carcinoma confirmed by CT-guided biopsy that was identical to the vulvar tumor. Conclusion. 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subjects	Carcinoma, Large Cell - pathology Carcinoma, Large Cell - secondary Female Humans Lung Neoplasms - pathology Metastatic lung carcinoma Middle Aged Vulvar lesions Vulvar Neoplasms - pathology Vulvar Neoplasms - secondary
title	Primary lung large cell carcinoma metastatic to the vulva: a case report and review of the literature
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