Decreased body mass index as an independent risk factor for developing chronic kidney disease

Background Obesity and metabolic syndrome are risk factors for the development of chronic kidney disease (CKD). Few studies have examined the effect of change in body mass index (ΔBMI) on CKD incidence in a general screening setting. Methods Subjects of this study were screenees that participated in...

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Bibliographic Details
Published in:Clinical and experimental nephrology 2009-02, Vol.13 (1), p.55-60
Main Authors: Tokashiki, Kaori, Tozawa, Masahiko, Iseki, Chiho, Kohagura, Kentaro, Kinjo, Kozen, Takishita, Shuichi, Iseki, Kunitoshi
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Body Mass Index
Chronic Disease
Creatinine - blood
Female
Glomerular Filtration Rate
Humans
Incidence
Kidney Diseases - diagnosis
Kidney Diseases - epidemiology
Kidney Diseases - etiology
Male
Mass Screening
Medicine
Medicine & Public Health
Middle Aged
Nephrology
Obesity - complications
Obesity - epidemiology
Odds Ratio
Original Article
Prevalence
Risk Assessment
Risk Factors
Sex Factors
Time Factors
Urology
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Summary:Background Obesity and metabolic syndrome are risk factors for the development of chronic kidney disease (CKD). Few studies have examined the effect of change in body mass index (ΔBMI) on CKD incidence in a general screening setting. Methods Subjects of this study were screenees that participated in the screening program of the Okinawa General Health Maintenance Association in 1993 and 2003 in Okinawa, Japan. Using identification number, birth date, sex, and other recorded identifiers, we identified 33,389 subjects among the 1993 screening participants ( N  = 143,948) who also participated in the 2003 screening. CKD was defined as estimated glomerular filtration rate
ISSN:1342-1751
1437-7799
DOI:10.1007/s10157-008-0085-y