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Monitoring perspiration from palms of hypohidrosis patients with a stopped-flow conductometric mini-system

Background: Sensitive and real-time methods are required to characterize the symptoms and resolve the complicated pathology of hypohidrosis. Method: We constructed a conductometric humidity sensor and a stopped-flow manifold with suitable dynamic range for monitoring impaired perspiration. The mini-...

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Bibliographic Details
Published in:Clinica chimica acta 2004-10, Vol.348 (1), p.107-111
Main Authors: Chang, Bin-Wha, Yeh, Shoou-Jeng, Tsai, Ping-Ping, Chang, Hsien-Chang
Format: Article
Language:English
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Summary:Background: Sensitive and real-time methods are required to characterize the symptoms and resolve the complicated pathology of hypohidrosis. Method: We constructed a conductometric humidity sensor and a stopped-flow manifold with suitable dynamic range for monitoring impaired perspiration. The mini-sensor was coated with a water-absorbing polymer of poly-(2-acrylamido-2-methylpropane sulfonate). Results: Perspiration from palms of normal individuals and hypohidrosis patients were monitored and compared. Tangent slopes of the sensorograms were capable of discriminating hypohidrosis patients from normal individuals. Conclusion: The conductometric min-sensor and the stopped-flow manifold were proven to be useful as a diagnostic tool for hypohidrosis.
ISSN:0009-8981
1873-3492
DOI:10.1016/j.cccn.2004.05.002