Micropapillary variant of transitional cell carcinoma of the bladder

A 77‐year‐old man visited the Kobe City General Hospital complaining of macroscopic hematuria. A computed tomography scan found a bladder tumor with left iliac and para‐aortic lymph node metastasis. Two courses of cisplatin, cyclophosphamide and doxorubicin chemotherapy resulted in a minimal respons...

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Bibliographic Details
Published in:International journal of urology 2004-09, Vol.11 (9), p.792-794
Main Authors: SUGINO, YOSHIO, NEGORO, HIROMITSU, IWAMURA, HIROSHI, MOROI, SEIJI, OKA, HIROYA, KAWAKITA, MUTSUSHI, HANIOKA, KEISUKE, TAKEUCHI, HIDEO
Format: Article
Language:English
Subjects:
Aged
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
bladder tumor
Carcinoma, Transitional Cell - diagnostic imaging
Carcinoma, Transitional Cell - drug therapy
Carcinoma, Transitional Cell - pathology
Carcinoma, Transitional Cell - surgery
chemotherapy
Fatal Outcome
Humans
Lymph Node Excision
lymph node metastasis
Lymphatic Metastasis
Male
micropapillary variant
Neoplasm Recurrence, Local
Reconstructive Surgical Procedures
Tomography, X-Ray Computed
transitional cell carcinoma
Urinary Bladder Neoplasms - diagnostic imaging
Urinary Bladder Neoplasms - drug therapy
Urinary Bladder Neoplasms - pathology
Urinary Bladder Neoplasms - surgery
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Description
Summary:A 77‐year‐old man visited the Kobe City General Hospital complaining of macroscopic hematuria. A computed tomography scan found a bladder tumor with left iliac and para‐aortic lymph node metastasis. Two courses of cisplatin, cyclophosphamide and doxorubicin chemotherapy resulted in a minimal response. Radical cystectomy and a retroperitoneal lymph node dissection with bilateral ureterocutaneostomy reconstruction were then performed. A pathological examination revealed a micropapillary variant of transitional cell carcinoma (Grade 3, pT1pN2M1). The patient died of pelvic recurrence 7 months after the initiation of chemotherapy. Peritonitis carcinomatosa and lung metastases were observed at autopsy.
ISSN:0919-8172
1442-2042
DOI:10.1111/j.1442-2042.2004.00880.x