Novel Platforms for Oral Drug Delivery

The aim of this review is to provide the reader general and inspiring prospects on recent and promising fields of innovation in oral drug delivery. Nowadays, inventive drug delivery systems vary from geometrically modified and modular matrices, more close to “classic” pharmaceutical manufacturing pr...

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Bibliographic Details
Published in:Pharmaceutical research 2009-03, Vol.26 (3), p.601-611
Main Authors: Colombo, P, Sonvico, F, Colombo, G, Bettini, R
Format: Article
Language:English
Subjects:
Administration, Oral
Biochemistry
Biological and medical sciences
Biomedical and Life Sciences
Biomedical Engineering and Bioengineering
Biomedicine
bioMEMS
combination therapy
Drug Carriers - chemistry
Drug delivery systems
Drug Delivery Systems - methods
Expert Review
General pharmacology
Medical Law
Medical sciences
Microelectromechanical systems
oral drug delivery
Pharmaceutical Preparations - administration & dosage
Pharmaceutical Preparations - chemistry
Pharmaceutical sciences
Pharmaceutical technology. Pharmaceutical industry
Pharmacology. Drug treatments
Pharmacology/Toxicology
Pharmacy
Polymers
smart polymers
swellable matrix
Tablets
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Summary:The aim of this review is to provide the reader general and inspiring prospects on recent and promising fields of innovation in oral drug delivery. Nowadays, inventive drug delivery systems vary from geometrically modified and modular matrices, more close to “classic” pharmaceutical manufacturing processes, to futuristic bio micro-electro-mechanical systems (bioMEMS), based on manufacturing techniques borrowed from electronics and other fields. In these technologies new materials and creative solutions are essential designing intelligent drug delivery systems able to release the required drug at the proper body location with the correct release rate. In particular, oral drug delivery systems of the future are expected to have a significant impact on the treatment of diseases, such as AIDS, cancer, malaria, diabetes requiring complex and multi-drug therapies, as well as on the life of patients, whose age and/or health status make necessary a multiple pharmacological approach.
ISSN:0724-8741
1573-904X
DOI:10.1007/s11095-008-9803-0