Loading…
Role of cyclooxygenase-1 and -2 in satellite cell proliferation, differentiation, and fusion
Skeletal muscle satellite cells play an important role in muscle regeneration. Previous work has suggested that nonsteroidal anti‐inflammatory drugs may inhibit their activity. We cultured skeletal muscle satellite cells from 9‐month‐old Sprague‐Dawley rats and exposed them to naproxen sodium (a non...
Saved in:
| Published in: | Muscle & nerve 2004-10, Vol.30 (4), p.497-500 |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c4902-566fc94f9376a53f3120a865657f0eaf9b040845a8a93b6ff837870ce6767b4c3 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c4902-566fc94f9376a53f3120a865657f0eaf9b040845a8a93b6ff837870ce6767b4c3 |
| container_end_page | 500 |
| container_issue | 4 |
| container_start_page | 497 |
| container_title | Muscle & nerve |
| container_volume | 30 |
| creator | Mendias, Christopher L. Tatsumi, Ryuichi Allen, Ronald E. |
| description | Skeletal muscle satellite cells play an important role in muscle regeneration. Previous work has suggested that nonsteroidal anti‐inflammatory drugs may inhibit their activity. We cultured skeletal muscle satellite cells from 9‐month‐old Sprague‐Dawley rats and exposed them to naproxen sodium (a nonselective cyclooxygenase inhibitor), NS‐398 (a selective cyclooxygenase‐2 inhibitor), and SC‐560 (a selective cyclooxygenase‐1 inhibitor) for 96 h. Cyclooxygenase‐2 inhibition alone resulted in decreased satellite cell proliferation, and inhibition of both cyclooxygenase‐1 and cyclooxygenase‐2 resulted in decreased satellite cell differentiation and fusion. This study suggests that the cyclooxygenase enzymes appear to play an important part in satellite cell proliferation, differentiation, and fusion and that nonsteroidal anti‐inflammatory medication may have an adverse effect on muscle regeneration following injury. The use of a selective cyclooxygenase‐2 inhibitor over nonspecific cyclooxygenase inhibitors in the treatment of muscle injuries is not supported. Muscle Nerve 30: 497–500, 2004 |
| doi_str_mv | 10.1002/mus.20102 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_66896492</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>66896492</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4902-566fc94f9376a53f3120a865657f0eaf9b040845a8a93b6ff837870ce6767b4c3</originalsourceid><addsrcrecordid>eNp1kF1LHDEUhkOx1FV74R8ouVEQOnryMfm4LItawSroilKEkM0mEp2d2U5m0P33Zt2pXnl1Pnje8x5ehHYJHBIAejTv0yEFAvQLGhHQsuClVhtoBISrQjB9t4m2UnoEAKKE_IY2Sckk5ZyM0P1VU3ncBOyWrmqal-WDr23yBcG2nuGC4ljjZDtfVbHz2OWKF21TxeBb28Wm_olnMeTB110cFith6FPud9DXYKvkvw91G92cHE_Gv4vzy9Oz8a_zwnENtCiFCE7zoJkUtmSBEQpWiVKUMoC3QU-Bg-KlVVazqQhBMakkOC-kkFPu2DbaX9_Nr_3rferMPKbVr7b2TZ-MEEoLrmkGD9aga5uUWh_Moo1z2y4NAbOK0uQozVuUmf0xHO2ncz_7IIfsMrA3ADY5W4XW1i6mD04QJokUmTtac8-x8svPHc2fm-v_1sVaEVPnX94Vtn0yQjJZmtuLUzOhFxN2d_vXjNkrSSuY-A</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>66896492</pqid></control><display><type>article</type><title>Role of cyclooxygenase-1 and -2 in satellite cell proliferation, differentiation, and fusion</title><source>Wiley</source><creator>Mendias, Christopher L. ; Tatsumi, Ryuichi ; Allen, Ronald E.</creator><creatorcontrib>Mendias, Christopher L. ; Tatsumi, Ryuichi ; Allen, Ronald E.</creatorcontrib><description>Skeletal muscle satellite cells play an important role in muscle regeneration. Previous work has suggested that nonsteroidal anti‐inflammatory drugs may inhibit their activity. We cultured skeletal muscle satellite cells from 9‐month‐old Sprague‐Dawley rats and exposed them to naproxen sodium (a nonselective cyclooxygenase inhibitor), NS‐398 (a selective cyclooxygenase‐2 inhibitor), and SC‐560 (a selective cyclooxygenase‐1 inhibitor) for 96 h. Cyclooxygenase‐2 inhibition alone resulted in decreased satellite cell proliferation, and inhibition of both cyclooxygenase‐1 and cyclooxygenase‐2 resulted in decreased satellite cell differentiation and fusion. This study suggests that the cyclooxygenase enzymes appear to play an important part in satellite cell proliferation, differentiation, and fusion and that nonsteroidal anti‐inflammatory medication may have an adverse effect on muscle regeneration following injury. The use of a selective cyclooxygenase‐2 inhibitor over nonspecific cyclooxygenase inhibitors in the treatment of muscle injuries is not supported. Muscle Nerve 30: 497–500, 2004</description><identifier>ISSN: 0148-639X</identifier><identifier>EISSN: 1097-4598</identifier><identifier>DOI: 10.1002/mus.20102</identifier><identifier>PMID: 15372441</identifier><identifier>CODEN: MUNEDE</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Animals ; Biological and medical sciences ; Blotting, Western ; Cell Differentiation - physiology ; Cell Division - physiology ; Cell Fusion ; Cells, Cultured ; Culture Media ; cyclooxygenase ; Cyclooxygenase 1 ; Cyclooxygenase 2 ; Cyclooxygenase 2 Inhibitors ; Cyclooxygenase Inhibitors ; Fundamental and applied biological sciences. Psychology ; Immunohistochemistry ; Isoenzymes - physiology ; Luminescent Measurements ; Male ; Membrane Proteins ; muscle regeneration ; Myogenin - biosynthesis ; Naproxen ; Nitrobenzenes ; NSAID ; prostaglandin ; Prostaglandin-Endoperoxide Synthases - physiology ; Pyrazoles ; Rats ; Rats, Sprague-Dawley ; satellite cell ; Satellite Cells, Skeletal Muscle - enzymology ; Satellite Cells, Skeletal Muscle - physiology ; Striated muscle. Tendons ; Sulfonamides ; Vertebrates: osteoarticular system, musculoskeletal system</subject><ispartof>Muscle & nerve, 2004-10, Vol.30 (4), p.497-500</ispartof><rights>Copyright © 2004 Wiley Periodicals, Inc.</rights><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4902-566fc94f9376a53f3120a865657f0eaf9b040845a8a93b6ff837870ce6767b4c3</citedby><cites>FETCH-LOGICAL-c4902-566fc94f9376a53f3120a865657f0eaf9b040845a8a93b6ff837870ce6767b4c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16137176$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15372441$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mendias, Christopher L.</creatorcontrib><creatorcontrib>Tatsumi, Ryuichi</creatorcontrib><creatorcontrib>Allen, Ronald E.</creatorcontrib><title>Role of cyclooxygenase-1 and -2 in satellite cell proliferation, differentiation, and fusion</title><title>Muscle & nerve</title><addtitle>Muscle Nerve</addtitle><description>Skeletal muscle satellite cells play an important role in muscle regeneration. Previous work has suggested that nonsteroidal anti‐inflammatory drugs may inhibit their activity. We cultured skeletal muscle satellite cells from 9‐month‐old Sprague‐Dawley rats and exposed them to naproxen sodium (a nonselective cyclooxygenase inhibitor), NS‐398 (a selective cyclooxygenase‐2 inhibitor), and SC‐560 (a selective cyclooxygenase‐1 inhibitor) for 96 h. Cyclooxygenase‐2 inhibition alone resulted in decreased satellite cell proliferation, and inhibition of both cyclooxygenase‐1 and cyclooxygenase‐2 resulted in decreased satellite cell differentiation and fusion. This study suggests that the cyclooxygenase enzymes appear to play an important part in satellite cell proliferation, differentiation, and fusion and that nonsteroidal anti‐inflammatory medication may have an adverse effect on muscle regeneration following injury. The use of a selective cyclooxygenase‐2 inhibitor over nonspecific cyclooxygenase inhibitors in the treatment of muscle injuries is not supported. Muscle Nerve 30: 497–500, 2004</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Blotting, Western</subject><subject>Cell Differentiation - physiology</subject><subject>Cell Division - physiology</subject><subject>Cell Fusion</subject><subject>Cells, Cultured</subject><subject>Culture Media</subject><subject>cyclooxygenase</subject><subject>Cyclooxygenase 1</subject><subject>Cyclooxygenase 2</subject><subject>Cyclooxygenase 2 Inhibitors</subject><subject>Cyclooxygenase Inhibitors</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Immunohistochemistry</subject><subject>Isoenzymes - physiology</subject><subject>Luminescent Measurements</subject><subject>Male</subject><subject>Membrane Proteins</subject><subject>muscle regeneration</subject><subject>Myogenin - biosynthesis</subject><subject>Naproxen</subject><subject>Nitrobenzenes</subject><subject>NSAID</subject><subject>prostaglandin</subject><subject>Prostaglandin-Endoperoxide Synthases - physiology</subject><subject>Pyrazoles</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><subject>satellite cell</subject><subject>Satellite Cells, Skeletal Muscle - enzymology</subject><subject>Satellite Cells, Skeletal Muscle - physiology</subject><subject>Striated muscle. Tendons</subject><subject>Sulfonamides</subject><subject>Vertebrates: osteoarticular system, musculoskeletal system</subject><issn>0148-639X</issn><issn>1097-4598</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><recordid>eNp1kF1LHDEUhkOx1FV74R8ouVEQOnryMfm4LItawSroilKEkM0mEp2d2U5m0P33Zt2pXnl1Pnje8x5ehHYJHBIAejTv0yEFAvQLGhHQsuClVhtoBISrQjB9t4m2UnoEAKKE_IY2Sckk5ZyM0P1VU3ncBOyWrmqal-WDr23yBcG2nuGC4ljjZDtfVbHz2OWKF21TxeBb28Wm_olnMeTB110cFith6FPud9DXYKvkvw91G92cHE_Gv4vzy9Oz8a_zwnENtCiFCE7zoJkUtmSBEQpWiVKUMoC3QU-Bg-KlVVazqQhBMakkOC-kkFPu2DbaX9_Nr_3rferMPKbVr7b2TZ-MEEoLrmkGD9aga5uUWh_Moo1z2y4NAbOK0uQozVuUmf0xHO2ncz_7IIfsMrA3ADY5W4XW1i6mD04QJokUmTtac8-x8svPHc2fm-v_1sVaEVPnX94Vtn0yQjJZmtuLUzOhFxN2d_vXjNkrSSuY-A</recordid><startdate>200410</startdate><enddate>200410</enddate><creator>Mendias, Christopher L.</creator><creator>Tatsumi, Ryuichi</creator><creator>Allen, Ronald E.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200410</creationdate><title>Role of cyclooxygenase-1 and -2 in satellite cell proliferation, differentiation, and fusion</title><author>Mendias, Christopher L. ; Tatsumi, Ryuichi ; Allen, Ronald E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4902-566fc94f9376a53f3120a865657f0eaf9b040845a8a93b6ff837870ce6767b4c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Blotting, Western</topic><topic>Cell Differentiation - physiology</topic><topic>Cell Division - physiology</topic><topic>Cell Fusion</topic><topic>Cells, Cultured</topic><topic>Culture Media</topic><topic>cyclooxygenase</topic><topic>Cyclooxygenase 1</topic><topic>Cyclooxygenase 2</topic><topic>Cyclooxygenase 2 Inhibitors</topic><topic>Cyclooxygenase Inhibitors</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Immunohistochemistry</topic><topic>Isoenzymes - physiology</topic><topic>Luminescent Measurements</topic><topic>Male</topic><topic>Membrane Proteins</topic><topic>muscle regeneration</topic><topic>Myogenin - biosynthesis</topic><topic>Naproxen</topic><topic>Nitrobenzenes</topic><topic>NSAID</topic><topic>prostaglandin</topic><topic>Prostaglandin-Endoperoxide Synthases - physiology</topic><topic>Pyrazoles</topic><topic>Rats</topic><topic>Rats, Sprague-Dawley</topic><topic>satellite cell</topic><topic>Satellite Cells, Skeletal Muscle - enzymology</topic><topic>Satellite Cells, Skeletal Muscle - physiology</topic><topic>Striated muscle. Tendons</topic><topic>Sulfonamides</topic><topic>Vertebrates: osteoarticular system, musculoskeletal system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mendias, Christopher L.</creatorcontrib><creatorcontrib>Tatsumi, Ryuichi</creatorcontrib><creatorcontrib>Allen, Ronald E.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Muscle & nerve</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mendias, Christopher L.</au><au>Tatsumi, Ryuichi</au><au>Allen, Ronald E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Role of cyclooxygenase-1 and -2 in satellite cell proliferation, differentiation, and fusion</atitle><jtitle>Muscle & nerve</jtitle><addtitle>Muscle Nerve</addtitle><date>2004-10</date><risdate>2004</risdate><volume>30</volume><issue>4</issue><spage>497</spage><epage>500</epage><pages>497-500</pages><issn>0148-639X</issn><eissn>1097-4598</eissn><coden>MUNEDE</coden><abstract>Skeletal muscle satellite cells play an important role in muscle regeneration. Previous work has suggested that nonsteroidal anti‐inflammatory drugs may inhibit their activity. We cultured skeletal muscle satellite cells from 9‐month‐old Sprague‐Dawley rats and exposed them to naproxen sodium (a nonselective cyclooxygenase inhibitor), NS‐398 (a selective cyclooxygenase‐2 inhibitor), and SC‐560 (a selective cyclooxygenase‐1 inhibitor) for 96 h. Cyclooxygenase‐2 inhibition alone resulted in decreased satellite cell proliferation, and inhibition of both cyclooxygenase‐1 and cyclooxygenase‐2 resulted in decreased satellite cell differentiation and fusion. This study suggests that the cyclooxygenase enzymes appear to play an important part in satellite cell proliferation, differentiation, and fusion and that nonsteroidal anti‐inflammatory medication may have an adverse effect on muscle regeneration following injury. The use of a selective cyclooxygenase‐2 inhibitor over nonspecific cyclooxygenase inhibitors in the treatment of muscle injuries is not supported. Muscle Nerve 30: 497–500, 2004</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>15372441</pmid><doi>10.1002/mus.20102</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0148-639X |
| ispartof | Muscle & nerve, 2004-10, Vol.30 (4), p.497-500 |
| issn | 0148-639X 1097-4598 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_66896492 |
| source | Wiley |
| subjects | Animals Biological and medical sciences Blotting, Western Cell Differentiation - physiology Cell Division - physiology Cell Fusion Cells, Cultured Culture Media cyclooxygenase Cyclooxygenase 1 Cyclooxygenase 2 Cyclooxygenase 2 Inhibitors Cyclooxygenase Inhibitors Fundamental and applied biological sciences. Psychology Immunohistochemistry Isoenzymes - physiology Luminescent Measurements Male Membrane Proteins muscle regeneration Myogenin - biosynthesis Naproxen Nitrobenzenes NSAID prostaglandin Prostaglandin-Endoperoxide Synthases - physiology Pyrazoles Rats Rats, Sprague-Dawley satellite cell Satellite Cells, Skeletal Muscle - enzymology Satellite Cells, Skeletal Muscle - physiology Striated muscle. Tendons Sulfonamides Vertebrates: osteoarticular system, musculoskeletal system |
| title | Role of cyclooxygenase-1 and -2 in satellite cell proliferation, differentiation, and fusion |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-13T02%3A56%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Role%20of%20cyclooxygenase-1%20and%20-2%20in%20satellite%20cell%20proliferation,%20differentiation,%20and%20fusion&rft.jtitle=Muscle%20&%20nerve&rft.au=Mendias,%20Christopher%20L.&rft.date=2004-10&rft.volume=30&rft.issue=4&rft.spage=497&rft.epage=500&rft.pages=497-500&rft.issn=0148-639X&rft.eissn=1097-4598&rft.coden=MUNEDE&rft_id=info:doi/10.1002/mus.20102&rft_dat=%3Cproquest_cross%3E66896492%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c4902-566fc94f9376a53f3120a865657f0eaf9b040845a8a93b6ff837870ce6767b4c3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=66896492&rft_id=info:pmid/15372441&rfr_iscdi=true |