Collagen Cross-linking and Ultimate Tensile Strength in Dentin

Several studies have indicated differences in bond strength of dental materials to crown and root dentin. To investigate the potential differences in matrix properties between these locations, we analyzed upper root and crown dentin in human third molars for ultimate tensile strength and collagen bi...

Full description

Saved in:
Bibliographic Details
Published in:Journal of dental research 2004-10, Vol.83 (10), p.807-810
Main Authors: Miguez, P.A., Pereira, P.N.R., Atsawasuwan, P., Yamauchi, M.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Analysis of Variance
Collagen - chemistry
Cross-Linking Reagents
Decalcification Technique
Dental Bonding
Dental Stress Analysis
Dentin - chemistry
Dentin - ultrastructure
Dentin Permeability
Dentistry
Humans
Molar
Space life sciences
Tensile Strength
Tooth Crown - chemistry
Tooth Root - chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c494t-c0ec24066517e558f82d6df5cecc8e3a5052853ffbe4fc1a105fadf6058b7a383
cites cdi_FETCH-LOGICAL-c494t-c0ec24066517e558f82d6df5cecc8e3a5052853ffbe4fc1a105fadf6058b7a383
container_end_page 810
container_issue 10
container_start_page 807
container_title Journal of dental research
container_volume 83
creator Miguez, P.A.
Pereira, P.N.R.
Atsawasuwan, P.
Yamauchi, M.
description Several studies have indicated differences in bond strength of dental materials to crown and root dentin. To investigate the potential differences in matrix properties between these locations, we analyzed upper root and crown dentin in human third molars for ultimate tensile strength and collagen biochemistry. In both locations, tensile strength tested perpendicular to the direction of dentinal tubules (undemineralized crown = 140.4 ± 48.6/root = 95.9 ± 26.1; demineralized crown = 16.6 ± 6.3/root = 29.0 ± 12.4) was greater than that tested parallel to the tubular direction (undemineralized crown = 73.1 ± 21.2/root = 63.2 ± 22.6; demineralized crown = 9.0 ± 3.9/root = 16.2 ± 8.0). The demineralized specimens showed significantly greater tensile strength in root than in crown. Although the collagen content was comparable in both locations, two major collagen cross-links, dehydrodihydroxylysinonorleucine/its ketoamine and pyridinoline, were significantly higher in the root (by ~ 30 and ~ 55%, respectively) when compared with those in the crown. These results indicate that the profile of collagen cross-linking varies as a function of anatomical location in dentin and that the difference may partly explain the site-specific tensile strength.
doi_str_mv 10.1177/154405910408301014
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_66898613</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_154405910408301014</sage_id><sourcerecordid>66898613</sourcerecordid><originalsourceid>FETCH-LOGICAL-c494t-c0ec24066517e558f82d6df5cecc8e3a5052853ffbe4fc1a105fadf6058b7a383</originalsourceid><addsrcrecordid>eNqFkU1Lw0AQhhdRbK3-AQ8SPHiLzuxHsrkIEj-h4MH2HNLNbE1NNzWbHPz3JrRQUNDTwPC878y8w9g5wjViHN-gkhJUgiBBC0BAecDGQzMcuodsDMB5CEKqETvxfgWACdfimI1QCY0xl2N2m9ZVlS_JBWlTex9Wpfso3TLIXRHMq7Zc5y0FM3K-rCh4axtyy_Y9KF1wT64t3Sk7snnl6WxXJ2z--DBLn8Pp69NLejcNjUxkGxogwyVEkcKYlNJW8yIqrDJkjCaRK1BcK2HtgqQ1mCMomxc2AqUXcS60mLCrre-mqT878m22Lr2hfnVHdeezKNKJjlD8C2IssF9kcLz8Aa7qrnH9ERmHRGqIedRDfAuZIZyGbLZp-kiarwwhG36Q_f5BL7rYOXeLNRV7yS70HrjZAr4Pfj_2D8tvGXmM1g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>209480726</pqid></control><display><type>article</type><title>Collagen Cross-linking and Ultimate Tensile Strength in Dentin</title><source>SAGE</source><creator>Miguez, P.A. ; Pereira, P.N.R. ; Atsawasuwan, P. ; Yamauchi, M.</creator><creatorcontrib>Miguez, P.A. ; Pereira, P.N.R. ; Atsawasuwan, P. ; Yamauchi, M.</creatorcontrib><description>Several studies have indicated differences in bond strength of dental materials to crown and root dentin. To investigate the potential differences in matrix properties between these locations, we analyzed upper root and crown dentin in human third molars for ultimate tensile strength and collagen biochemistry. In both locations, tensile strength tested perpendicular to the direction of dentinal tubules (undemineralized crown = 140.4 ± 48.6/root = 95.9 ± 26.1; demineralized crown = 16.6 ± 6.3/root = 29.0 ± 12.4) was greater than that tested parallel to the tubular direction (undemineralized crown = 73.1 ± 21.2/root = 63.2 ± 22.6; demineralized crown = 9.0 ± 3.9/root = 16.2 ± 8.0). The demineralized specimens showed significantly greater tensile strength in root than in crown. Although the collagen content was comparable in both locations, two major collagen cross-links, dehydrodihydroxylysinonorleucine/its ketoamine and pyridinoline, were significantly higher in the root (by ~ 30 and ~ 55%, respectively) when compared with those in the crown. These results indicate that the profile of collagen cross-linking varies as a function of anatomical location in dentin and that the difference may partly explain the site-specific tensile strength.</description><identifier>ISSN: 0022-0345</identifier><identifier>EISSN: 1544-0591</identifier><identifier>DOI: 10.1177/154405910408301014</identifier><identifier>PMID: 15381724</identifier><identifier>CODEN: JDREAF</identifier><language>eng</language><publisher>United States: SAGE Publications</publisher><subject>Adolescent ; Adult ; Analysis of Variance ; Collagen - chemistry ; Cross-Linking Reagents ; Decalcification Technique ; Dental Bonding ; Dental Stress Analysis ; Dentin - chemistry ; Dentin - ultrastructure ; Dentin Permeability ; Dentistry ; Humans ; Molar ; Space life sciences ; Tensile Strength ; Tooth Crown - chemistry ; Tooth Root - chemistry</subject><ispartof>Journal of dental research, 2004-10, Vol.83 (10), p.807-810</ispartof><rights>International and American Associations for Dental Research</rights><rights>Copyright American Association for Dental Research/American Academy of Implant Dentistry Oct 2004</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c494t-c0ec24066517e558f82d6df5cecc8e3a5052853ffbe4fc1a105fadf6058b7a383</citedby><cites>FETCH-LOGICAL-c494t-c0ec24066517e558f82d6df5cecc8e3a5052853ffbe4fc1a105fadf6058b7a383</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925,79364</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15381724$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Miguez, P.A.</creatorcontrib><creatorcontrib>Pereira, P.N.R.</creatorcontrib><creatorcontrib>Atsawasuwan, P.</creatorcontrib><creatorcontrib>Yamauchi, M.</creatorcontrib><title>Collagen Cross-linking and Ultimate Tensile Strength in Dentin</title><title>Journal of dental research</title><addtitle>J Dent Res</addtitle><description>Several studies have indicated differences in bond strength of dental materials to crown and root dentin. To investigate the potential differences in matrix properties between these locations, we analyzed upper root and crown dentin in human third molars for ultimate tensile strength and collagen biochemistry. In both locations, tensile strength tested perpendicular to the direction of dentinal tubules (undemineralized crown = 140.4 ± 48.6/root = 95.9 ± 26.1; demineralized crown = 16.6 ± 6.3/root = 29.0 ± 12.4) was greater than that tested parallel to the tubular direction (undemineralized crown = 73.1 ± 21.2/root = 63.2 ± 22.6; demineralized crown = 9.0 ± 3.9/root = 16.2 ± 8.0). The demineralized specimens showed significantly greater tensile strength in root than in crown. Although the collagen content was comparable in both locations, two major collagen cross-links, dehydrodihydroxylysinonorleucine/its ketoamine and pyridinoline, were significantly higher in the root (by ~ 30 and ~ 55%, respectively) when compared with those in the crown. These results indicate that the profile of collagen cross-linking varies as a function of anatomical location in dentin and that the difference may partly explain the site-specific tensile strength.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Analysis of Variance</subject><subject>Collagen - chemistry</subject><subject>Cross-Linking Reagents</subject><subject>Decalcification Technique</subject><subject>Dental Bonding</subject><subject>Dental Stress Analysis</subject><subject>Dentin - chemistry</subject><subject>Dentin - ultrastructure</subject><subject>Dentin Permeability</subject><subject>Dentistry</subject><subject>Humans</subject><subject>Molar</subject><subject>Space life sciences</subject><subject>Tensile Strength</subject><subject>Tooth Crown - chemistry</subject><subject>Tooth Root - chemistry</subject><issn>0022-0345</issn><issn>1544-0591</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><recordid>eNqFkU1Lw0AQhhdRbK3-AQ8SPHiLzuxHsrkIEj-h4MH2HNLNbE1NNzWbHPz3JrRQUNDTwPC878y8w9g5wjViHN-gkhJUgiBBC0BAecDGQzMcuodsDMB5CEKqETvxfgWACdfimI1QCY0xl2N2m9ZVlS_JBWlTex9Wpfso3TLIXRHMq7Zc5y0FM3K-rCh4axtyy_Y9KF1wT64t3Sk7snnl6WxXJ2z--DBLn8Pp69NLejcNjUxkGxogwyVEkcKYlNJW8yIqrDJkjCaRK1BcK2HtgqQ1mCMomxc2AqUXcS60mLCrre-mqT878m22Lr2hfnVHdeezKNKJjlD8C2IssF9kcLz8Aa7qrnH9ERmHRGqIedRDfAuZIZyGbLZp-kiarwwhG36Q_f5BL7rYOXeLNRV7yS70HrjZAr4Pfj_2D8tvGXmM1g</recordid><startdate>20041001</startdate><enddate>20041001</enddate><creator>Miguez, P.A.</creator><creator>Pereira, P.N.R.</creator><creator>Atsawasuwan, P.</creator><creator>Yamauchi, M.</creator><general>SAGE Publications</general><general>SAGE PUBLICATIONS, INC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RQ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>U9A</scope><scope>7QP</scope><scope>7X8</scope></search><sort><creationdate>20041001</creationdate><title>Collagen Cross-linking and Ultimate Tensile Strength in Dentin</title><author>Miguez, P.A. ; Pereira, P.N.R. ; Atsawasuwan, P. ; Yamauchi, M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c494t-c0ec24066517e558f82d6df5cecc8e3a5052853ffbe4fc1a105fadf6058b7a383</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Analysis of Variance</topic><topic>Collagen - chemistry</topic><topic>Cross-Linking Reagents</topic><topic>Decalcification Technique</topic><topic>Dental Bonding</topic><topic>Dental Stress Analysis</topic><topic>Dentin - chemistry</topic><topic>Dentin - ultrastructure</topic><topic>Dentin Permeability</topic><topic>Dentistry</topic><topic>Humans</topic><topic>Molar</topic><topic>Space life sciences</topic><topic>Tensile Strength</topic><topic>Tooth Crown - chemistry</topic><topic>Tooth Root - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Miguez, P.A.</creatorcontrib><creatorcontrib>Pereira, P.N.R.</creatorcontrib><creatorcontrib>Atsawasuwan, P.</creatorcontrib><creatorcontrib>Yamauchi, M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Career &amp; Technical Education Database</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>Health Medical collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>Proquest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Biological Sciences</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Biological Science Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of dental research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Miguez, P.A.</au><au>Pereira, P.N.R.</au><au>Atsawasuwan, P.</au><au>Yamauchi, M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Collagen Cross-linking and Ultimate Tensile Strength in Dentin</atitle><jtitle>Journal of dental research</jtitle><addtitle>J Dent Res</addtitle><date>2004-10-01</date><risdate>2004</risdate><volume>83</volume><issue>10</issue><spage>807</spage><epage>810</epage><pages>807-810</pages><issn>0022-0345</issn><eissn>1544-0591</eissn><coden>JDREAF</coden><abstract>Several studies have indicated differences in bond strength of dental materials to crown and root dentin. To investigate the potential differences in matrix properties between these locations, we analyzed upper root and crown dentin in human third molars for ultimate tensile strength and collagen biochemistry. In both locations, tensile strength tested perpendicular to the direction of dentinal tubules (undemineralized crown = 140.4 ± 48.6/root = 95.9 ± 26.1; demineralized crown = 16.6 ± 6.3/root = 29.0 ± 12.4) was greater than that tested parallel to the tubular direction (undemineralized crown = 73.1 ± 21.2/root = 63.2 ± 22.6; demineralized crown = 9.0 ± 3.9/root = 16.2 ± 8.0). The demineralized specimens showed significantly greater tensile strength in root than in crown. Although the collagen content was comparable in both locations, two major collagen cross-links, dehydrodihydroxylysinonorleucine/its ketoamine and pyridinoline, were significantly higher in the root (by ~ 30 and ~ 55%, respectively) when compared with those in the crown. These results indicate that the profile of collagen cross-linking varies as a function of anatomical location in dentin and that the difference may partly explain the site-specific tensile strength.</abstract><cop>United States</cop><pub>SAGE Publications</pub><pmid>15381724</pmid><doi>10.1177/154405910408301014</doi><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0022-0345
ispartof Journal of dental research, 2004-10, Vol.83 (10), p.807-810
issn 0022-0345
1544-0591
language eng
recordid cdi_proquest_miscellaneous_66898613
source SAGE
subjects Adolescent
Adult
Analysis of Variance
Collagen - chemistry
Cross-Linking Reagents
Decalcification Technique
Dental Bonding
Dental Stress Analysis
Dentin - chemistry
Dentin - ultrastructure
Dentin Permeability
Dentistry
Humans
Molar
Space life sciences
Tensile Strength
Tooth Crown - chemistry
Tooth Root - chemistry
title Collagen Cross-linking and Ultimate Tensile Strength in Dentin
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T09%3A32%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Collagen%20Cross-linking%20and%20Ultimate%20Tensile%20Strength%20in%20Dentin&rft.jtitle=Journal%20of%20dental%20research&rft.au=Miguez,%20P.A.&rft.date=2004-10-01&rft.volume=83&rft.issue=10&rft.spage=807&rft.epage=810&rft.pages=807-810&rft.issn=0022-0345&rft.eissn=1544-0591&rft.coden=JDREAF&rft_id=info:doi/10.1177/154405910408301014&rft_dat=%3Cproquest_cross%3E66898613%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c494t-c0ec24066517e558f82d6df5cecc8e3a5052853ffbe4fc1a105fadf6058b7a383%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=209480726&rft_id=info:pmid/15381724&rft_sage_id=10.1177_154405910408301014&rfr_iscdi=true