Connexins: Gaps in Our Knowledge of Vascular Function

Xavier F. Figueroa , Brant E. Isakson and Brian R. Duling Department of Molecular Physiology and Biological Physics, Cardiovascular Research Center, University of Virginia, Charlottesville, Virginia 22908 Gap junctions are common features in the vasculature, long thought to provide a pathway for cel...

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Bibliographic Details
Published in:Physiology (Bethesda, Md.) Md.), 2004-10, Vol.19 (5), p.277-284
Main Authors: Figueroa, Xavier F, Isakson, Brant E, Duling, Brian R
Format: Article
Language:English
Subjects:
Animals
Blood Vessels - physiology
Connexins - physiology
Gap Junctions - physiology
Humans
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Summary:Xavier F. Figueroa , Brant E. Isakson and Brian R. Duling Department of Molecular Physiology and Biological Physics, Cardiovascular Research Center, University of Virginia, Charlottesville, Virginia 22908 Gap junctions are common features in the vasculature, long thought to provide a pathway for cell-cell signaling. Emerging understanding of the gap-junctional proteins (connexins) and new tools for their investigation now offer the opportunity to explore the vital role that the gap junctions may play in cardiovascular homeostasis and pathophysiology.
ISSN:1548-9213
1548-9221
DOI:10.1152/physiol.00008.2004