Biomarkers of cardiovascular disease risk in 40–65-year-old men performing recommended levels of physical activity, compared with sedentary men

Objective:Both the UK Department of Health and the US Centers for Disease Control and Prevention have recommended at least 30 minutes of moderate-intensity physical activity on most days for health. Specific mention is made of beneficial effects upon blood lipids. The purpose of this study was to co...

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Bibliographic Details
Published in:British journal of sports medicine 2009-02, Vol.43 (2), p.136-141
Main Authors: Perkins, G M, Owen, A, Kearney, E M, Swaine, I L
Format: Article
Language:English
Subjects:
Adult
Aged
Apolipoproteins
Apolipoproteins - blood
Biomarkers
Biomarkers - blood
Cardiovascular disease
Cardiovascular Diseases - prevention & control
Cholesterol
Cholesterol - blood
Comparative analysis
Cross-Sectional Studies
Disease control
Exercise
Exercise - physiology
Heart rate
Humans
Lipids
Lipoproteins
Male
Men
Mens health
Middle Aged
Physical fitness
Questionnaires
Ratios
Risk Factors
Studies
Triglycerides
Triglycerides - blood
Variables
Walking
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Summary:Objective:Both the UK Department of Health and the US Centers for Disease Control and Prevention have recommended at least 30 minutes of moderate-intensity physical activity on most days for health. Specific mention is made of beneficial effects upon blood lipids. The purpose of this study was to compare biomarkers of cardiovascular disease risk in men who perform physical activity in accordance with these recommendations with those who do not.Methods:128 healthy men, aged 40–65 years, were recruited. 61 were classified as active (performing at least the minimum recommended physical activity of ⩾4 metabolic equivalents (METs), for 6 months immediately before the study) and 67 as sedentary. Fasting blood was drawn for total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), triglycerides, and apolipoproteins (Apo) A-1 and B. Low-density lipoprotein cholesterol (LDL-C) was estimated using the Friedewald equation.Results:The median (interquartile range) physical activity level was 7.0 (5.0–10.7) versus 1.0 (0–1.8) hour/week at ⩾4 METs (active versus sedentary; p
ISSN:0306-3674
1473-0480
DOI:10.1136/bjsm.2007.044420