Effect of oxytocin on neuronal activity in amygdaloid nuclei in stressed rats

The dynamics of impulse activity of amygdaloid neurons in response to intravenous injection of oxytocin were examined in acute experiments on random-bred albino rats. Oxytocin modified activity of amygdaloid neurons in intact and stressed rats. The dose-dependent effects of oxytocin were manifested...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2004-06, Vol.137 (6), p.563-565
Main Authors: Mukhitdinova, Kh N, Stamova, L G, Rasulov, M M
Format: Article
Language:English
Subjects:
Amygdala - cytology
Amygdala - metabolism
Animals
Dose-Response Relationship, Drug
Electrophysiology
Female
Neurons - drug effects
Neurons - metabolism
Oxytocin - administration & dosage
Oxytocin - pharmacology
Rats
Stress, Psychological
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Summary:The dynamics of impulse activity of amygdaloid neurons in response to intravenous injection of oxytocin were examined in acute experiments on random-bred albino rats. Oxytocin modified activity of amygdaloid neurons in intact and stressed rats. The dose-dependent effects of oxytocin were manifested in changes in the latency of neuronal responses and in rearrangement of their spike activity. The oxytocin-induced neuronal responses were less pronounced in cells with high baseline activity.
ISSN:0007-4888
1573-8221
DOI:10.1023/B:BEBM.0000042712.69412.bf