Contrast-enhanced ultrasound and liver imaging: review of the literature

The advent of second-generation microbubble ultrasound contrast agents and the development of contrast specific ultrasound techniques improved the ability of contrast enhanced ultrasound (CEUS) in detecting and characterizing focal liver lesions, opening new prospects in liver imaging. A Medline sea...

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Bibliographic Details
Published in:Journal de radiologie 2009-01, Vol.90 (1 Pt 2), p.93-106; quiz 107-8
Main Authors: Ladam-Marcus, V, Mac, G, Job, L, Piot-Veron, S, Marcus, C, Hoeffel, C
Format: Article
Language:fre
Subjects:
Adult
Contrast Media
Diagnosis, Differential
Fatty Liver - diagnostic imaging
Female
Focal Nodular Hyperplasia - diagnostic imaging
Humans
Image Enhancement
Liver - diagnostic imaging
Liver Neoplasms - diagnostic imaging
Liver Neoplasms - secondary
Male
Microbubbles
Middle Aged
Practice Guidelines as Topic
Sensitivity and Specificity
Ultrasonography - methods
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Summary:The advent of second-generation microbubble ultrasound contrast agents and the development of contrast specific ultrasound techniques improved the ability of contrast enhanced ultrasound (CEUS) in detecting and characterizing focal liver lesions, opening new prospects in liver imaging. A Medline search in June 2008 identified 72 published studies that used CEUS in focal liver lesion detection, characterization, and follow-up to monitor tumor ablation procedures and antiangiogenic treatment. The purpose of this paper, based on literature review, is to describe the technical recommendations when using CEUS for liver imaging and to define the different vascular patterns of the most relevant benign and malignant lesions. Diagnostic performance of CEUS and the important clinical indications are also presented and discussed. CEUS is increasingly accepted in clinical use for diagnostic imaging and post-interventional workup liver imaging. It may replace many computed tomography and magnetic resonance imaging examinations in the near future, according to the European Federation of Societies for Ultrasound in Medicine and Biology guidelines.
ISSN:0221-0363
DOI:10.1016/S0221-0363(09)70087-3