Effects of pineal peptides on circadian dynamics of spermatogonia proliferation in albino rats

Mitotic index of type B spermatogonia in intact animals is characterized by a circadian rhythm. Mitotic index increased and its circadian rhythm disappeared after pinealectomy. Treatment with Epithalamin for 14 days restored the circadian rhythm. The circadian biorhythm of spermatogonia proliferatio...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2004-06, Vol.137 (6), p.597-600
Main Authors: Arav, V I, Sych, V F, Zheleznyak, E V, Slesarev, S M
Format: Article
Language:English
Subjects:
Animals
Antineoplastic Agents - pharmacology
Circadian Rhythm - drug effects
Male
Mitosis - physiology
Peptides - pharmacology
Photoperiod
Pineal Gland - chemistry
Pineal Gland - surgery
Rats
Spermatogonia - cytology
Spermatogonia - drug effects
Spermatogonia - physiology
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Summary:Mitotic index of type B spermatogonia in intact animals is characterized by a circadian rhythm. Mitotic index increased and its circadian rhythm disappeared after pinealectomy. Treatment with Epithalamin for 14 days restored the circadian rhythm. The circadian biorhythm of spermatogonia proliferation suggests the presence of circadian rhythm of spermatogenesis in general and its regulation by the pineal gland.
ISSN:0007-4888
1573-8221
DOI:10.1023/B:BEBM.0000042722.66262.de