Thrombosis of temporal artery and renal vein in Kimura disease related nephrotic syndrome

• Published in: Journal of thrombosis and thrombolysis 2009-01, Vol.27 (1), p.115-118
• Main Authors: Danis, Ramazan, Ozmen, Sehmus, Akin, Davut, Ozekinci, Selver, Altintas, Abdullah, Cil, Timucin, Pasa, Semir, Kılınc, Ilhan
• Format: Article
• Language: English
• Subjects: Angiolymphoid Hyperplasia with Eosinophilia - blood; Angiolymphoid Hyperplasia with Eosinophilia - complications; Angiolymphoid Hyperplasia with Eosinophilia - diagnosis; Arterial Occlusive Diseases - etiology; Arterial Occlusive Diseases - surgery; Cardiology; Diagnosis, Differential; Eosinophilia - etiology; Glomerulonephritis, Membranous - etiology; Hematology; Humans; Immunoglobulin E - blood; Magnetic Resonance Imaging; Medicine; Medicine & Public Health; Nephrotic Syndrome - etiology; Renal Veins - pathology; Temporal Arteries - pathology; Temporal Arteries - surgery; Thrombosis - etiology; Turkey - epidemiology; Venous Thrombosis - etiology
• ISSN: 0929-5305; 1573-742X
• DOI: 10.1007/s11239-007-0178-6

Kimura disease (KD) is an angiolymphoid proliferative disorder of unknown etiology, occurs mainly in Asian patients, presenting with subcutaneous slowly growing masses, with a predilection for preauricular and submandibular regions . The clinical course of the disease is thought to be benign. Concomitant peripheral blood eosinophilia and elevated serum immunoglobulin E levels are often observed. Main systemic manifestation of the KD is renal involvement. Renal abnormalities, notably proteinuria and nephrotic syndrome have been found to be associated with KD. We report a 42-year-old man with KD and a steroid-sensitive membraneous nephrotic syndrome with bilaterally temporal artery and renal vein thrombosis. This is the first reported case of KD associated nephrotic syndrome complicated with wide arterial and venous thrombosis from Anatolia.