Multimodality imaging: an update on PET/CT technology

Introduction Since their introduction in 2001, PET/CT systems have gained wide acceptance primarily due to their inherent ability to combine functional and structural information about the underlying disease state of the patient in a single imaging session. Their significance has also been documente...

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Bibliographic Details
Published in:European journal of nuclear medicine and molecular imaging 2009-03, Vol.36 (Suppl 1), p.15-29
Main Authors: Mawlawi, Osama, Townsend, David W.
Format: Article
Language:English
Subjects:
Animals
Cardiology
Equipment Design
Humans
Imaging
Magnetic Resonance Imaging - trends
Medical imaging
Medicine
Medicine & Public Health
Nuclear Medicine
Oncology
Orthopedics
Positron-Emission Tomography - instrumentation
Positron-Emission Tomography - methods
Positron-Emission Tomography - trends
Radiology
Tomography
Tomography, X-Ray Computed - instrumentation
Tomography, X-Ray Computed - methods
Tomography, X-Ray Computed - trends
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Summary:Introduction Since their introduction in 2001, PET/CT systems have gained wide acceptance primarily due to their inherent ability to combine functional and structural information about the underlying disease state of the patient in a single imaging session. Their significance has also been documented with regard to their short imaging times, which minimize patient anxiety and image blurring due to patient motion. In the past seven years, PET/CT systems have replaced dedicated PET systems as the imaging modality of choice for diagnostic evaluation of oncology patients. Objectives The purpose of this article is to review the evolution of PET/CT systems and document their current status. Discussion Recent improvements in instrumentation are highlighted together with some outstanding issues that arise for specific PET/CT applications. These are followed by a description of some of the more common clinical applications of PET/CT imaging such as staging malignant disease, treatment planning, and monitoring therapy response. Finally, the future developments of PET/CT systems with regard to sensitivity, resolution, and new radiopharmaceuticals are discussed. The article concludes by presenting some issues concerning the next stage in the future of PET imaging, namely PET/MRI.
ISSN:1619-7070
1619-7089
DOI:10.1007/s00259-008-1016-6