Decreased perinatal mortality among women with diet-controlled gestational diabetes mellitus

Abstract Objective To examine pregnancy outcomes associated with diet-controlled gestational diabetes mellitus (GDM A1). Methods A retrospective cohort study compared pregnancy characteristics of women with and without GDM A1 at a center where GDM A1 patients are routinely induced at 40 weeks. Resul...

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Bibliographic Details
Published in:International journal of gynecology and obstetrics 2009-03, Vol.104 (3), p.199-202
Main Authors: Karmon, Anatte, Levy, Amalia, Holcberg, Gershon, Wiznitzer, Arnon, Mazor, Moshe, Sheiner, Eyal
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Cesarean delivery
Cohort Studies
Diabetes, Gestational - diet therapy
Diabetes, Gestational - epidemiology
Female
Gestational Age
Gestational diabetes mellitus
Glucose Tolerance Test
Gynecology. Andrology. Obstetrics
Humans
Incidence
Induction
Infant
Infant, Newborn
Israel - epidemiology
Maternal Age
Medical sciences
Obstetrics and Gynecology
Perinatal mortality
Perinatal Mortality - trends
Pregnancy
Pregnancy in Diabetics - epidemiology
Pregnancy Outcome - epidemiology
Retrospective Studies
Risk Factors
Young Adult
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Summary:Abstract Objective To examine pregnancy outcomes associated with diet-controlled gestational diabetes mellitus (GDM A1). Methods A retrospective cohort study compared pregnancy characteristics of women with and without GDM A1 at a center where GDM A1 patients are routinely induced at 40 weeks. Results Higher rates of complications such as shoulder dystocia, congenital malformation, and macrosomia were observed in GDM A1 patients. A lower incidence of perinatal mortality was present in GDM A1 women compared with women without GDM A1. This association lost its significance when controlled for maternal age, ethnicity, induction, cesarean delivery, and birth weight in a multivariate model. Although the stillbirth rate before 40 weeks of gestation was identical among all participants, after 40 weeks it was significantly higher in women without GDM A1. Conclusion Induction of women with GDM A1 at 40 weeks may play a role in lowering perinatal mortality to below that of the general population.
ISSN:0020-7292
1879-3479
DOI:10.1016/j.ijgo.2008.09.016