Synthesis of benzothiazoles via ipso substitution of ortho-methoxythiobenzamides

An efficient route to the synthesis of benzothiazoles from ortho-methoxythiobenzamides via the ipso substitution of an aromatic methoxy group is presented, and the mechanism of the Jacobson synthesis of benzothiazoles is further investigated.

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Bibliographic Details
Published in:Organic & biomolecular chemistry 2004-10, Vol.2 (20), p.3039-3043
Main Authors: Downer, Nadale K, Jackson, Yvette A
Format: Article
Language:English
Subjects:
Benzamides - chemistry
Benzothiazoles - chemical synthesis
Models, Chemical
Molecular Structure
Online Access:Get full text
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Description
Summary:An efficient route to the synthesis of benzothiazoles from ortho-methoxythiobenzamides via the ipso substitution of an aromatic methoxy group is presented, and the mechanism of the Jacobson synthesis of benzothiazoles is further investigated.
ISSN:1477-0520
DOI:10.1039/B410373D