Esophageal atresia and achalasialike esophageal dysmotility

A 14-year-old boy presented with regurgitation, malnutrition, and chronic lung insufficiency with a history of successful repair of esophageal atresia and tracheoesophageal fistula in the newborn period. Barium swallow and manometry results showed achalasia. Hellar operation with antireflux procedur...

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Bibliographic Details
Published in:Journal of pediatric surgery 2004-10, Vol.39 (10), p.1581-1583
Main Authors: Cheng, W., Poon, K.H., Lui, V.C.H., Yong, J.L., Law, S., So, K.T., Tse, K., Tam, P.K.H.
Format: Article
Language:English
Subjects:
Achalasia
Adolescent
Esophageal Achalasia - diagnosis
Esophageal Achalasia - etiology
Esophageal Achalasia - pathology
esophageal atresia
Esophageal Atresia - complications
Esophageal Atresia - surgery
Humans
Infant, Newborn
Male
Tracheoesophageal Fistula - complications
Tracheoesophageal Fistula - surgery
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Description
Summary:A 14-year-old boy presented with regurgitation, malnutrition, and chronic lung insufficiency with a history of successful repair of esophageal atresia and tracheoesophageal fistula in the newborn period. Barium swallow and manometry results showed achalasia. Hellar operation with antireflux procedure resulted in complete symptomatic relief. Histology and immunohistochemistry including PGP9.5, MAP5, cKit, and nNOS of myotomy specimen showed intact innervation. Although esophageal dysmotility after esophageal atresia repair usually is caused by gastroesophageal reflux and incoordination of peristalsis, the possibility of achalasia should also be considered, because a casual relationship between esophageal atresia and achalasia may exist.
ISSN:0022-3468
1531-5037
DOI:10.1016/j.jpedsurg.2004.06.027