Anti- Helicobacter pylori activity of plants used in Mexican traditional medicine for gastrointestinal disorders

Helicobacter pylori is the major etiological agent of chronic active gastritis and peptic ulcer disease and is linked to gastric carcinoma. Treatment to eradicate the bacteria failed in many cases, mainly due to antibiotic resistance, hence the necessity of developing better therapeutic regimens. Me...

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Bibliographic Details
Published in:Journal of ethnopharmacology 2009-03, Vol.122 (2), p.402-405
Main Authors: Castillo-Juárez, Israel, González, Violeta, Jaime-Aguilar, Héctor, Martínez, Gisela, Linares, Edelmira, Bye, Robert, Romero, Irma
Format: Article
Language:English
Subjects:
Animals
Annona cherimola
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
Antibacterial activity
antibacterial properties
Aqueous extract
Artemisia ludoviciana
Biological and medical sciences
Cuphea
Cuphea aequipetala
digestive system diseases
Gastritis
Gastrointestinal Diseases - drug therapy
Gastrointestinal Diseases - microbiology
General pharmacology
Guaiacum
Guaiacum coulteri
Helicobacter Infections - drug therapy
Helicobacter pylori
Helicobacter pylori - drug effects
in vitro studies
Ludwigia
Ludwigia repens
Magnoliopsida
Medical sciences
medicinal plants
medicinal properties
Medicine, Traditional
Mentha piperita
Methanol extract
Mexican medicinal plants
Mexico
microbial activity
Microbial Sensitivity Tests
minimum inhibitory concentration
Moussonia deppeana
peptic ulcers
Persea americana
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phytotherapy
plant extracts
Plant Extracts - pharmacology
Plant Extracts - therapeutic use
Plants, Medicinal
stomach neoplasms
traditional medicine
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Description
Summary:Helicobacter pylori is the major etiological agent of chronic active gastritis and peptic ulcer disease and is linked to gastric carcinoma. Treatment to eradicate the bacteria failed in many cases, mainly due to antibiotic resistance, hence the necessity of developing better therapeutic regimens. Mexico has an enormous unexplored potential of medicinal plants. This work evaluates the in vitro anti- H. pylori activity of 53 plants used in Mexican traditional medicine for gastrointestinal disorders. To test the in vitro antibacterial activity, agar dilution and broth dilution methods were used for aqueous and methanolic extracts, respectively. Aqueous extracts of Artemisia ludoviciana subsp. mexicana, Cuphea aequipetala, Ludwigia repens,and Mentha × piperita (MIC 125 to
ISSN:0378-8741
1872-7573
DOI:10.1016/j.jep.2008.12.021