Continuous autonomic assessment in patients with symptomatic heart failure: Prognostic value of Heart rate variability measured by an implanted cardiac resynchronization device

Heart rate variability (HRV) as an indirect autonomic assessment provides prognostic information when measured over short time periods in patients with heart failure. Long-term continuous HRV can be measured from an implantable device, but the clinical value of these measurements is unknown. A total...

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Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 2004-10, Vol.110 (16), p.2389-2394
Main Authors: ADAMSON, Philip B, SMITH, Andrew L, ABRAHAM, William T, KLECKNER, Karen J, STADLER, Robert W, SHIH, Alex, RHODES, Melissa M
Format: Article
Language:English
Subjects:
Aged
Algorithms
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Autonomic Nervous System - physiopathology
Biological and medical sciences
Blood and lymphatic vessels
Cardiology. Vascular system
Circadian Rhythm
Defibrillators, Implantable
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Emergency and intensive care: renal failure. Dialysis management
Female
Follow-Up Studies
Heart
Heart Conduction System - physiopathology
Heart Failure - mortality
Heart Failure - physiopathology
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Heart Rate
Hospitalization - statistics & numerical data
Humans
Intensive care medicine
Life Tables
Male
Medical sciences
Middle Aged
Models, Cardiovascular
Monitoring, Physiologic - instrumentation
Monitoring, Physiologic - methods
Motor Activity
Prognosis
Risk Assessment
Survival Analysis
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Description
Summary:Heart rate variability (HRV) as an indirect autonomic assessment provides prognostic information when measured over short time periods in patients with heart failure. Long-term continuous HRV can be measured from an implantable device, but the clinical value of these measurements is unknown. A total of 397 patients with New York Heart Association class III or IV heart failure were studied. Of these, 370 patients had information from their implanted cardiac resynchronization device for mortality risk stratification, and 288 patients had information for measured parameters (ie, HRV, night heart rate, and patient activity) and clinical event analyses. Continuous HRV was measured as the standard deviation of 5-minute median atrial-atrial intervals (SDAAM) sensed by the device. SDAAM
ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.0000139841.42454.78