Cardiovascular Disease Parameters in Periodontitis

Background: Recently, there has been an increasing in the impact of oral health on atherosclerosis and subsequent cardiovascular disease. The aim of this study is to investigate the association between chronic periodontitis and cardiovascular risk markers. Methods: Forty patients with periodontitis...

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Bibliographic Details
Published in:Journal of periodontology (1970) 2009-03, Vol.80 (3), p.378-388
Main Authors: Monteiro, Andréa M., Jardini, Maria A.N., Alves, Sarah, Giampaoli, Viviana, Aubin, Elisete C.Q., Figueiredo Neto, Antônio M., Gidlund, Magnus
Format: Article
Language:English
Subjects:
Adult
Age Factors
Antibodies
Antibodies - blood
atherosclerosis
Atherosclerosis (general aspects, experimental research)
Biological and medical sciences
Blood and lymphatic vessels
Body Mass Index
Cardiology. Vascular system
cardiovascular
Case-Control Studies
Cholesterol - blood
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Cholesterol, LDL - immunology
Chronic Periodontitis - complications
Coronary Artery Disease - complications
Dentistry
Facial bones, jaws, teeth, parodontium: diseases, semeiology
Female
Humans
Hypercholesterolemia - complications
Hypertriglyceridemia - complications
Interleukin-6 - blood
Interleukin-8 - blood
Leukocyte Count
Lipid Peroxides - blood
Lipoproteins, LDL - blood
Male
Medical sciences
Middle Aged
Neutrophils - pathology
Non tumoral diseases
Otorhinolaryngology. Stomatology
Oxidation-Reduction
oxLDL
periodontitis
Refractometry
Risk Factors
Sex Factors
Thiobarbituric Acid Reactive Substances - analysis
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Summary:Background: Recently, there has been an increasing in the impact of oral health on atherosclerosis and subsequent cardiovascular disease. The aim of this study is to investigate the association between chronic periodontitis and cardiovascular risk markers. Methods: Forty patients with periodontitis and 40 healthy gender‐, body mass index–, and age‐matched individuals were compared by measuring total cholesterol, high‐density lipoprotein, low‐density lipoprotein, triglycerides, levels of cytokines, antibodies against oxidized low‐density lipoprotein, thiobarbituric acid reactive substances, total and differential white blood cell counts, and the non‐linear index of refraction. Results: The levels of triglycerides and high‐density lipoprotein in periodontitis patients were significantly higher and lower, respectively (P = 0.002 and P = 0.0126), compared to controls. Total cholesterol, low‐density lipoprotein, and lipid peroxide levels were the same in both groups (P = 0.2943, P = 0.1284, and P = 0.067, respectively). Interleukin (IL)‐6 and −8, antibodies against oxidized low‐density lipoprotein, and leukocyte and neutrophil counts were significantly higher in periodontitis patients (P
ISSN:0022-3492
1943-3670
DOI:10.1902/jop.2009.080431