Pericardial patch repair of the left atrioventricular valve in atrioventricular septal defect: long-term changes in the patch

Abstract A 31-year-old woman with partial atrioventricular septal defect underwent left atrioventricular valve (LAVV) replacement. Her initial repair was at 8 years of age. At 23 years of age, she underwent reoperation due to a combination of severe left ventricular outlet obstruction and moderate L...

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Bibliographic Details
Published in:Cardiovascular pathology 2009-03, Vol.18 (2), p.119-122
Main Authors: Luk, Adriana, Ahn, Eric, Soor, Gursharan S, Williams, William G, Mezody, Melitta, Butany, Jagdish
Format: Article
Language:English
Subjects:
Adult
Animals
Atrioventricular septal defect
Bovine pericardial patch
Calcinosis
Cattle
Female
Heart Septal Defects, Atrial - surgery
Heart Septal Defects, Ventricular - surgery
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation - methods
Heart Valves - pathology
Heart Valves - surgery
Humans
Mitral valve insufficiency and repair
Pathology
Pericardium - surgery
Pericardium - transplantation
Polyethylene Terephthalates
Reoperation
Transplantation, Heterologous
Treatment Outcome
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Summary:Abstract A 31-year-old woman with partial atrioventricular septal defect underwent left atrioventricular valve (LAVV) replacement. Her initial repair was at 8 years of age. At 23 years of age, she underwent reoperation due to a combination of severe left ventricular outlet obstruction and moderate LAVV regurgitation. At that reoperation, she had a Dacron patch enlargement of the infundibular septum and repair of her LAVV with a xenograft (bovine) pericardial patch sutured into the superior bridging leaflet. LAVV replacement was required 8 years later because of valve insufficiency. There was a perforation in the patch with fibrosis, thickening due to pannus, and calcification of the pericardial tissue and the leaflet tissue, leading to stiffening of the tissue.
ISSN:1054-8807
1879-1336
DOI:10.1016/j.carpath.2007.12.006